Literature DB >> 1251187

Brain acetylcholine: control by dietary choline.

E L Cohen, R J Wurtman.   

Abstract

Acetylcholine concentrations in whole rat brain or in various brain regions and free choline concentrations in blood serum and brain vary with dietary choline consumption. The increases in brain acetylcholine after treatment with physositigmine (an inhibitor of actylcholinesterase) or after consumption of a diet high in choline are additive, suggesting that choline acts by increasing acetylcholine synthesis.

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Year:  1976        PMID： 1251187     DOI： 10.1126/science.1251187

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  47 in total

1.  Impaired de novo choline synthesis explains why phosphatidylethanolamine N-methyltransferase-deficient mice are protected from diet-induced obesity.

Authors:  René L Jacobs; Yang Zhao; Debby P Y Koonen; Torunn Sletten; Brian Su; Susanne Lingrell; Guoqing Cao; David A Peake; Ming-Shang Kuo; Spencer D Proctor; Brian P Kennedy; Jason R B Dyck; Dennis E Vance
Journal:  J Biol Chem       Date:  2010-05-07       Impact factor: 5.157

2.  Cerebrospinal fluid acetylcholine and choline in vascular dementia of Binswanger and multiple small infarct types as compared with Alzheimer-type dementia.

Authors:  H Tohgi; T Abe; M Kimura; M Saheki; S Takahashi
Journal:  J Neural Transm (Vienna)       Date:  1996       Impact factor: 3.575

3.  A brief history of choline.

Authors:  Steven H Zeisel
Journal:  Ann Nutr Metab       Date:  2012-11-26       Impact factor: 3.374

4.  Choline availability modulates the expression of TGFbeta1 and cytoskeletal proteins in the hippocampus of developing rat brain.

Authors:  C D Albright; A Y Tsai; M H Mar; S H Zeisel
Journal:  Neurochem Res       Date:  1998-05       Impact factor: 3.996

5.  Effect of theanine, r-glutamylethylamide, on brain monoamines and striatal dopamine release in conscious rats.

Authors:  H Yokogoshi; M Kobayashi; M Mochizuki; T Terashima
Journal:  Neurochem Res       Date:  1998-05       Impact factor: 3.996

6.  An analysis of licking microstructure in three strains of mice.

Authors:  A W Johnson; A Sherwood; D R Smith; M Wosiski-Kuhn; M Gallagher; P C Holland
Journal:  Appetite       Date:  2009-12-16       Impact factor: 3.868

7.  [Glutamate and GABA concentration in the brain and cerebrospinal fluid of rats treated with phosphatidylcholine].

Authors:  D Claus; J S Kim; J C Aschoff; H H Kornhuber
Journal:  Arch Psychiatr Nervenkr (1970)       Date:  1982

8.  Myasthenic syndrome: effect of choline, plasmapheresis and tests for circulating factor.

Authors:  H Kranz; D J Caddy; A M Williams; W Gay
Journal:  J Neurol Neurosurg Psychiatry       Date:  1980-06       Impact factor: 10.154

9.  Transport of nutrients and hormones through the blood-brain barrier.

Authors:  W M Pardridge
Journal:  Diabetologia       Date:  1981-03       Impact factor: 10.122

10.  Ethanol-induced increase in brain concentrations of administered neutral amino acids.

Authors:  T Eriksson; A Carlsson
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1980-10       Impact factor: 3.000
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