Literature DB >> 6994205

High-pressure liquid chromatography for quantitation of antimicrobial agents.

T T Yoshikawa, S K Maitra, M C Schotz, L B Guze.   

Abstract

Several methods are currently available for quantitation of antimicrobial drugs in serum and body fluids, e.g., microbiological, radioenzymatic, and radioimmune assays. Recently, high-pressure liquid chromatography (HPLC) has been implemented for quantitation of a variety of drugs, including antimicrobial drugs. The general principles of chromatography, particularly in reference to HPLC, are reviewed. The methods and procedures for extraction, separation, detection, and quantitation of antimicrobial drugs by HPLC are discussed. Current HPLC techniques for measuring antimicrobial drugs in biological fluids are also summarized.

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Year:  1980        PMID： 6994205     DOI： 10.1093/clinids/2.2.169

Source DB:  PubMed          Journal:  Rev Infect Dis        ISSN： 0162-0886


  10 in total

1.  Evaluation of separation and purification processes in the antibiotic industry. Scientific note.

Authors:  P R Bienkowski; D D Lee; C H Byers
Journal:  Appl Biochem Biotechnol       Date:  1988-08       Impact factor: 2.926

2.  Anion-exchange extraction of cephapirin, cefotaxime, and cefoxitin from serum for liquid chromatography.

Authors:  C E Fasching; L R Peterson
Journal:  Antimicrob Agents Chemother       Date:  1982-04       Impact factor: 5.191

3.  Liquid chromatographic assay of ceftizoxime in sera of normal and uremic patients.

Authors:  E M McCormick; R M Echols; T G Rosano
Journal:  Antimicrob Agents Chemother       Date:  1984-03       Impact factor: 5.191

4.  Comparison of an HPLC method with a RIA, EMIT and FIA method for the assay of serum gentamicin with extensive statistical evaluation.

Authors:  W Hospes; R J Boskma; J R Brouwers
Journal:  Pharm Weekbl Sci       Date:  1982-04-23

5.  Concentrations of sulbactam/ampicillin in serum and lung tissue.

Authors:  U Frank; E Schmidt-Eisenlohr; A Joos-Württemberger; J Hasse; F Daschner
Journal:  Infection       Date:  1990 Sep-Oct       Impact factor: 3.553

6.  The penetration of antibiotics into human pancreas.

Authors:  M Büchler; P Malfertheiner; H Friess; R Bittner; E Vanek; P Schlegel; H G Beger
Journal:  Infection       Date:  1989 Jan-Feb       Impact factor: 3.553

7.  High-pressure liquid chromatographic analysis of aztreonam in sera and urine.

Authors:  F G Pilkiewicz; B J Remsburg; S M Fisher; R B Sykes
Journal:  Antimicrob Agents Chemother       Date:  1983-06       Impact factor: 5.191

8.  High-pressure liquid chromatographic method for analysis of cephalosporins.

Authors:  S A Signs; T M File; J S Tan
Journal:  Antimicrob Agents Chemother       Date:  1984-11       Impact factor: 5.191

Review 9.  Clinical pharmacokinetics of the third generation cephalosporins.

Authors:  L Balant; P Dayer; R Auckenthaler
Journal:  Clin Pharmacokinet       Date:  1985 Mar-Apr       Impact factor: 6.447

Review 10.  Serum level monitoring of antibacterial drugs. A review.

Authors:  M Wenk; S Vozeh; F Follath
Journal:  Clin Pharmacokinet       Date:  1984 Nov-Dec       Impact factor: 6.447
  10 in total

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