Literature DB >> 6991440

Transfer of group A streptococcal pyrogenic exotoxin production to nontoxigenic strains of lysogenic conversion.

L P Johnson, P M Schlievert, D W Watson.   

Abstract

Production of group A streptococcal pyrogenic exotoxins (SPE) type A and C was transferred from toxigenic streptococcal strains to nontoxigenic strains by lysogeny. Lysogens were tested for SPE with Ouchterlony immunodiffusion on Todd-Hewitt agar plates; toxin diffusing from isolated colonies reacted with specific hyperimmune antisera to SPE. Phage prepared from strains T25(3) (T12gl) and 3GL16, both yielding SPE type A, formed plaques on T25(3) (NONLYSOGENIC) lawns. Over 90% of the colonies picked from the plaque centers yielded A toxin, suggesting SPE type A was transferred by lysogenic conversion. SPE type C formation was transferred to nontoxigenic strains T25(3) and K56 with supernatant fluids from mitomycin C-induced cultures of CS112, producing SPE types B and C. All lysogens tested were positive for SPE type C, indicating that C toxin induction also was transferred by lysogenic conversion. SPE type B formation was not transferable by lysogeny with the strains tested.

Entities:  

Mesh：

Substances：

Year:  1980        PMID： 6991440      PMCID： PMC550920          DOI： 10.1128/iai.28.1.254-257.1980

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  10 in total

1.  Reinterpretation of the Dick test: role of group A streptococcal pyrogenic exotoxin.

Authors:  P M Schlievert; K M Bettin; D W Watson
Journal:  Infect Immun       Date:  1979-11       Impact factor: 3.441

2.  Nonspecific T-lymphocyte mitogenesis by pyrogenic exotoxins from group A streptococci and Staphylococcus aureus.

Authors:  P M Schlievert; D J Schoettle; D W Watson
Journal:  Infect Immun       Date:  1979-09       Impact factor: 3.441

3.  Heterogeneity of group A streptococcal pyrogenic exotoxin type B.

Authors:  E L Barsumian; C M Cunningham; P M Schlievert; D W Watson
Journal:  Infect Immun       Date:  1978-05       Impact factor: 3.441

4.  Purification and characterization of group A streptococcal pyrogenic exotoxin type C.

Authors:  P M Schlievert; K M Bettin; D W Watson
Journal:  Infect Immun       Date:  1977-05       Impact factor: 3.441

5.  Further purification of group A streptococcal pyrogenic exotoxin and characterization of the purified toxin.

Authors:  C M Cunningham; E L Barsumian; D W Watson
Journal:  Infect Immun       Date:  1976-09       Impact factor: 3.441

6.  Group A streptococcal pyrogenic exotoxin: pyrogenicity, alteration of blood-brain barrier, and separation of sites for pyrogenicity and enhancement of lethal endotoxin shock.

Authors:  P M Schlievert; D W Watson
Journal:  Infect Immun       Date:  1978-09       Impact factor: 3.441

7.  A purified group A streptococcal pyrogenic exotoxin. Physiochemical and biological properties including the enhancement of susceptibility to endotoxin lethal shock.

Authors:  Y B Kim; D W Watson
Journal:  J Exp Med       Date:  1970-03-01       Impact factor: 14.307

8.  Intergroup phage reactions and transduction between group C and group A streptococci.

Authors:  L W Wannamaker; S Almquist; S Skjold
Journal:  J Exp Med       Date:  1973-06-01       Impact factor: 14.307

9.  Host-parasite factors in group A streptococcal infections. Pyrogenic and other effects of immunologic distinct exotoxins related to scarlet fever toxins.

Authors:  D W WATSON
Journal:  J Exp Med       Date:  1960-02-01       Impact factor: 14.307

10.  THE ROLE OF TEMPERATE BACTERIOPHAGE IN THE PRODUCTION OF ERYTHROGENIC TOXIN BY GROUP A STREPTOCOCCI.

Authors:  J B ZABRISKIE
Journal:  J Exp Med       Date:  1964-05-01       Impact factor: 14.307
  10 in total
  16 in total

Review 1.  Bacteriophages in the evolution of pathogen-host interactions.

Authors:  E A Miao; S I Miller
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-17       Impact factor: 11.205

2.  Nucleotide sequence of the staphylococcal enterotoxin C1 gene and relatedness to other pyrogenic toxins.

Authors:  G A Bohach; P M Schlievert
Journal:  Mol Gen Genet       Date:  1987-08

3.  Bacteriophage involvement in group A streptococcal pyrogenic exotoxin A production.

Authors:  L P Johnson; M A Tomai; P M Schlievert
Journal:  J Bacteriol       Date:  1986-05       Impact factor: 3.490

4.  Group A streptococcal phage T12 carries the structural gene for pyrogenic exotoxin type A.

Authors:  L P Johnson; P M Schlievert
Journal:  Mol Gen Genet       Date:  1984

5.  A physical map of the group A streptococcal pyrogenic exotoxin bacteriophage T12 genome.

Authors:  L P Johnson; P M Schlievert
Journal:  Mol Gen Genet       Date:  1983

6.  Phage influence on the synthesis of extracellular toxins in group A streptococci.

Authors:  S K Nida; J J Ferretti
Journal:  Infect Immun       Date:  1982-05       Impact factor: 3.441

7.  Phage-host interactions and the production of type A streptococcal exotoxin in group A streptococci.

Authors:  L McKane; J J Ferretti
Journal:  Infect Immun       Date:  1981-12       Impact factor: 3.441

8.  The gene for type A streptococcal exotoxin (erythrogenic toxin) is located in bacteriophage T12.

Authors:  C R Weeks; J J Ferretti
Journal:  Infect Immun       Date:  1984-11       Impact factor: 3.441

9.  Characterization of an inducible bacteriophage from a leukotoxic strain of Actinobacillus actinomycetemcomitans.

Authors:  R H Stevens; B F Hammond; C H Lai
Journal:  Infect Immun       Date:  1982-01       Impact factor: 3.441

10.  Cloning and characterization of the gene, speC, for pyrogenic exotoxin type C from Streptococcus pyogenes.

Authors:  S C Goshorn; G A Bohach; P M Schlievert
Journal:  Mol Gen Genet       Date:  1988-04
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.