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Literature DB >> 6982607

The anti-inflammatory action of nepitrin, a flavonoid.

Abstract

The anti-inflammatory efficacy of nepitrin (5,3',4'-trihydroxy-6-methoxy flavone), a flavonoid, was investigated in both acute and chronic models of inflammation in rats. Nepitrin was found to possess significant anti-inflammatory activity in the exudative and proliferative phases of inflammation. This action of nepitrin could be due to its anti-bradykinin and anti-angiotensin action. Nepitrin also possessed anti-pyretic and weak analgesic activity. The study reveals that nepitrin may be useful as an anti-inflammatory and anti-arthritic agent.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1982 PMID： 6982607 DOI： 10.1007/BF01965393

Source DB: PubMed Journal: Agents Actions ISSN： 0065-4299

14 in total

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7 in total

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4. The antioxidant effects of the flavonoids rutin and quercetin inhibit oxaliplatin-induced chronic painful peripheral neuropathy.

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6. Phenolic acids and flavonoids from Salvia plebeia and HPLC-UV profiling of four Salvia species.

Authors: Leo Adrianne Paje; Jungwon Choi; Hak-Dong Lee; Juree Kim; A Ram Yu; Min-Jung Bae; Paul John L Geraldino; Sanghyun Lee
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Authors: Patrícia I C Godinho; Raquel G Soengas; Vera L M Silva
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7 in total