Literature DB >> 6979715

Sequence homology and structural comparison between the chromosomal human alpha 1-antitrypsin and chicken ovalbumin genes.

M Leicht, G L Long, T Chandra, K Kurachi, V J Kidd, M Mace, E W Davie, S L Woo.   

Abstract

The human chromosomal alpha 1-antitrypsin gene has been cloned. This gene is approximately 5 kilobase pairs long and contains three intervening sequences in the peptide-coding region. DNA sequences coding for the amino and carboxyl termini of a alpha 1-antitrypsin have been identified. Human alpha 1-antitrypsin and chicken ovalbumin show significant sequences homology and belong to a common protein super-family. Yet the number, position and size of intervening sequences reveal that the two genes are dissimilar.

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Year:  1982        PMID： 6979715     DOI： 10.1038/297655a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  30 in total

1.  Distal trisomy 14q. II. Molecular study of the 14q32 locus in two cases of chromosome 14 rearrangements with partial duplication.

Authors:  G Keyeux; S Gilgenkrantz; G Lefranc; M P Lefranc
Journal:  Hum Genet       Date:  1990-10       Impact factor: 4.132

2.  Characterization of the gene and protein of the common alpha 1-antitrypsin normal M2 allele.

Authors:  T Nukiwa; M L Brantly; F Ogushi; G A Fells; R G Crystal
Journal:  Am J Hum Genet       Date:  1988-09       Impact factor: 11.025

3.  RNA splicing permits expression of a maize gene with a defective Suppressor-mutator transposable element insertion in an exon.

Authors:  H Y Kim; J W Schiefelbein; V Raboy; D B Furtek; O E Nelson
Journal:  Proc Natl Acad Sci U S A       Date:  1987-08       Impact factor: 11.205

4.  Do exons code for structural or functional units in proteins?

Authors:  T W Traut
Journal:  Proc Natl Acad Sci U S A       Date:  1988-05       Impact factor: 11.205

5.  A genetic locus closely linked to a protease inhibitor gene complex controls the level of multiple RNA transcripts.

Authors:  R E Hill; P H Shaw; R K Barth; N D Hastie
Journal:  Mol Cell Biol       Date:  1985-08       Impact factor: 4.272

6.  Organization of the human alpha 2-plasmin inhibitor gene.

Authors:  S Hirosawa; Y Nakamura; O Miura; Y Sumi; N Aoki
Journal:  Proc Natl Acad Sci U S A       Date:  1988-09       Impact factor: 11.205

Review 7.  Are proteins made of modules?

Authors:  T W Traut
Journal:  Mol Cell Biochem       Date:  1986-04       Impact factor: 3.396

8.  Chromosomal localization of the human alpha 1-antitrypsin gene (PI) to 14q31-32.

Authors:  W T Schroeder; M F Miller; S L Woo; G F Saunders
Journal:  Am J Hum Genet       Date:  1985-09       Impact factor: 11.025

9.  Nucleotide sequence and expression of human chromosome 21-encoded superoxide dismutase mRNA.

Authors:  L Sherman; N Dafni; J Lieman-Hurwitz; Y Groner
Journal:  Proc Natl Acad Sci U S A       Date:  1983-09       Impact factor: 11.205

10.  Evidence of normal functional levels of activated protein C inhibitor in combined Factor V/VIII deficiency disease.

Authors:  W M Canfield; W Kisiel
Journal:  J Clin Invest       Date:  1982-12       Impact factor: 14.808
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