Literature DB >> 697955

Immunologic sex differences and the female predominance in systemic lupus erythematosus.

R D Inman.   

Abstract

The female predominance in many rheumatic disorders, most notably systemic lupus erythematosus, suggests that immunologic sex differences may modify susceptibility to disease. Clinical and experimental data indicate heightened humoral immunity and depressed cellular immunity in females compared with males. These differences appear to be mediated by sex hormones.

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Year:  1978        PMID： 697955     DOI： 10.1002/art.1780210718

Source DB:  PubMed          Journal:  Arthritis Rheum        ISSN： 0004-3591


  29 in total

1.  Effect of hormone replacement therapy on post-menopausal changes of lymphocytes and T cell subsets.

Authors:  M Kamada; M Irahara; M Maegawa; T Yasui; T Takeji; M Yamada; M Tezuka; Y Kasai; T Aono
Journal:  J Endocrinol Invest       Date:  2000-06       Impact factor: 4.256

Review 2.  Sexual dimorphism in innate immune responses to infectious organisms.

Authors:  Ian Marriott; Yvette M Huet-Hudson
Journal:  Immunol Res       Date:  2006       Impact factor: 2.829

Review 3.  Sex hormone modulation in systemic lupus erythematosus: still a therapeutic option?

Authors:  R A Asherson; R G Lahita
Journal:  Ann Rheum Dis       Date:  1991-12       Impact factor: 19.103

4.  Low free testosterone levels in rheumatoid arthritis.

Authors:  T D Spector; L A Perry; G Tubb; A J Silman; E C Huskisson
Journal:  Ann Rheum Dis       Date:  1988-01       Impact factor: 19.103

5.  Effects of sex steroids on immunoglobulin M production by Epstein-Barr virus-transformed B-cell line SKW6-CL4.

Authors:  H Mori; M Sawairi; N Itoh; T Hanabayashi; T Tamaya
Journal:  J In Vitro Fert Embryo Transf       Date:  1991-12

6.  Free and serum testosterone levels in 276 males: a comparative study of rheumatoid arthritis, ankylosing spondylitis and healthy controls.

Authors:  T D Spector; W Ollier; L A Perry; A J Silman; P W Thompson; A Edwards
Journal:  Clin Rheumatol       Date:  1989-03       Impact factor: 2.980

7.  Enigmatic sex disparities in cancer incidence.

Authors:  Gustaf Edgren; Liming Liang; Hans-Olov Adami; Ellen T Chang
Journal:  Eur J Epidemiol       Date:  2012-01-03       Impact factor: 8.082

8.  Estrogen deficiency accelerates autoimmune exocrinopathy in murine Sjögren's syndrome through fas-mediated apoptosis.

Authors:  N Ishimaru; K Saegusa; K Yanagi; N Haneji; I Saito; Y Hayashi
Journal:  Am J Pathol       Date:  1999-07       Impact factor: 4.307

9.  Stimulation of anti-RNP antibody binding to cultured keratinocytes by estradiol.

Authors:  F Furukawa; S Imamura; D A Norris
Journal:  Arch Dermatol Res       Date:  1991       Impact factor: 3.017

10.  The relationship between genetics and environment in the pathogenesis of rheumatic diseases.

Authors:  A Calin
Journal:  West J Med       Date:  1979-09
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