Literature DB >> 6971725

Tumor detection with 1-aminocyclopentane and 1-aminocyclobutane C-11-carboxylic acid using positron emission computerized tomography.

K F Hübner, S Krauss, L C Washburn, W D Gibbs, E C Holloway.   

Abstract

Eight patients with proven or suspected neoplastic lesions were examined with 1-aminocyclobutane C-11-carboxylic acid and 1-aminocyclopentane C-11-carboxylic acid using positron emission computed tomography. The results of this comparative study have shown that both of these unnatural amino acids have a high affinity for malignant tumors. The potential of nonmetabolizable C-11-labeled amino acids as noninvasive indicators of metabolic tumor activity is demonstrated and discussed.

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Year:  1981        PMID: 6971725     DOI: 10.1097/00003072-198106000-00004

Source DB:  PubMed          Journal:  Clin Nucl Med        ISSN: 0363-9762            Impact factor:   7.794


  8 in total

Review 1.  The development, past achievements, and future directions of brain PET.

Authors:  Terry Jones; Eugenii A Rabiner
Journal:  J Cereb Blood Flow Metab       Date:  2012-03-21       Impact factor: 6.200

2.  Pilot evaluation of anti-1-amino-2-[18F] fluorocyclopentane-1-carboxylic acid (anti-2-[18F] FACPC) PET-CT in recurrent prostate carcinoma.

Authors:  Bital Savir-Baruch; David M Schuster; Nashwa Jarkas; Viraj A Master; Peter T Nieh; Raghuveer K Halkar; Jonathon A Nye; Melinda M Lewis; Ronald J Crowe; Ronald J Voll; Vernon M Camp; Leah M Bellamy; David L Roberts; Mark M Goodman
Journal:  Mol Imaging Biol       Date:  2011-12       Impact factor: 3.488

3.  Evaluation of [1-11C]-alpha-aminoisobutyric acid for tumor detection and amino acid transport measurement: spontaneous canine tumor studies.

Authors:  R E Bigler; P B Zanzonico; B Schmall; P S Conti; J R Dahl; L Rothman; G Sgouros; E G MacEwen
Journal:  Eur J Nucl Med       Date:  1985

Review 4.  Positron emission tomography imaging of prostate cancer.

Authors:  Hao Hong; Yin Zhang; Jiangtao Sun; Weibo Cai
Journal:  Amino Acids       Date:  2009-11-28       Impact factor: 3.520

5.  Tumor detection with carbon-11-labelled amino acids.

Authors:  K Kubota; K Yamada; H Fukada; S Endo; M Ito; Y Abe; T Yamaguchi; T Fujiwara; T Sato; K Ito
Journal:  Eur J Nucl Med       Date:  1984

6.  Uptake of 11C-L- and D-methionine in brain tumors.

Authors:  G J Meyer; O Schober; H Hundeshagen
Journal:  Eur J Nucl Med       Date:  1985

7.  Synthesis, Radiolabeling, and Biological Evaluation of the trans-Stereoisomers of 1-Amino-3-(fluoro-18F)-4-fluorocyclopentane-1-carboxylic Acid as PET Imaging Agents.

Authors:  Thomas C Pickel; Gouthami Pashikanti; Ronald J Voll; Weiping Yu; Zhaobin Zhang; Jonathon A Nye; John Bacsa; Jeffrey J Olson; Lanny S Liebeskind; Mark M Goodman
Journal:  ACS Pharmacol Transl Sci       Date:  2021-04-05

8.  Kinetic evaluation of 11C-1-aminocyclopentane carboxylic acid in rabbits bearing VX-2 tumors using positron emission tomography.

Authors:  T Fujiwara; T Matsuzawa; H Kawai; R Kawashima; M Itoh; S Watanuki; T Takahashi; R Iwata; T Ido
Journal:  Jpn J Cancer Res       Date:  1989-12
  8 in total

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