Literature DB >> 6941270

Nucleotide sequence of the 26S mRNA of Sindbis virus and deduced sequence of the encoded virus structural proteins.

C M Rice, J H Strauss.   

Abstract

The nucleotide sequence of intracellular 26S mRNA of Sindbis virus has been determined by direct sequence analysis of the cDNA made to this RNA with reverse transcriptase. From this, the amino acid sequences of the encoded virus structural proteins, which include a basic capsid protein and two integral membrane glycoproteins, have been deduced. The features of these proteins as related to their functions are discussed. We suggest that three proteases are required to produce these proteins from their polyprotein precursor: a viral protease, which functions in the cytosol to release the capsid protein, signalase, which makes two cleavages to separate the glycoproteins; and a protease of the Golgi complex that cleaves after double basic residues, to process the precursor form of one of the glycoproteins.

Entities:  

Mesh：

Substances：

Year:  1981        PMID： 6941270      PMCID： PMC319283          DOI： 10.1073/pnas.78.4.2062

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  28 in total

1.  Cleavage of Rous sarcoma viral polypeptide precursor into internal structural proteins in vitro involves viral protein p15.

Authors:  K von der Helm
Journal:  Proc Natl Acad Sci U S A       Date:  1977-03       Impact factor: 11.205

2.  The 5'-terminal leader sequence of late 16 S mRNA from cells infected with simian virus 40.

Authors:  P K Ghosh; V B Reddy; J Swinscoe; P V Choudary; P Lebowitz; S M Weissman
Journal:  J Biol Chem       Date:  1978-05-25       Impact factor: 5.157

3.  Complete nucleotide sequence of SV40 DNA.

Authors:  W Fiers; R Contreras; G Haegemann; R Rogiers; A Van de Voorde; H Van Heuverswyn; J Van Herreweghe; G Volckaert; M Ysebaert
Journal:  Nature       Date:  1978-05-11       Impact factor: 49.962

4.  Isolation and characterization of the membrane proteins of Semliki Forest virus.

Authors:  H Garoff; K Simons; O Renkonen
Journal:  Virology       Date:  1974-10       Impact factor: 3.616

5.  Virus-directed post-translational cleavage in Sindbus virus-infected cells.

Authors:  R K Schupham; K J Jones; B P Sagik; H R Bose
Journal:  J Virol       Date:  1977-05       Impact factor: 5.103

6.  The capsid protein of Semliki Forest virus has clusters of basic amino acids and prolines in its amino-terminal region.

Authors:  H Garoff; A M Frischauf; K Simons; H Lehrach; H Delius
Journal:  Proc Natl Acad Sci U S A       Date:  1980-11       Impact factor: 11.205

7.  Antigenic characterization of two sindbis envelope glycoproteins separated by isoelectric focusing.

Authors:  J M Dalrymple; S Schlesinger; P K Russell
Journal:  Virology       Date:  1976-01       Impact factor: 3.616

8.  How a single Sindbis virus mRNA directs the synthesis of one soluble protein and two integral membrane glycoproteins.

Authors:  D F Wirth; F Katz; B Small; H F Lodish
Journal:  Cell       Date:  1977-02       Impact factor: 41.582

9.  Purification and composition of the proteins from Sindbis virus grown in chick and BHK cells.

Authors:  D J Burke; K Keegstra
Journal:  J Virol       Date:  1976-12       Impact factor: 5.103

10.  Glycoproteins of Sindbis virus: priliminary characterization of the oligosaccharides.

Authors:  B M Sefton; K Keegstra
Journal:  J Virol       Date:  1974-09       Impact factor: 5.103
View more
  157 in total

1.  Locations of carbohydrate sites on alphavirus glycoproteins show that E1 forms an icosahedral scaffold.

Authors:  Sergei V Pletnev; Wei Zhang; Suchetana Mukhopadhyay; Bonnie R Fisher; Raquel Hernandez; Dennis T Brown; Timothy S Baker; Michael G Rossmann; Richard J Kuhn
Journal:  Cell       Date:  2001-04-06       Impact factor: 41.582

2.  Low-pH-dependent fusion of Sindbis virus with receptor-free cholesterol- and sphingolipid-containing liposomes.

Authors:  J M Smit; R Bittman; J Wilschut
Journal:  J Virol       Date:  1999-10       Impact factor: 5.103

3.  Cis-acting RNA elements at the 5' end of Sindbis virus genome RNA regulate minus- and plus-strand RNA synthesis.

Authors:  I Frolov; R Hardy; C M Rice
Journal:  RNA       Date:  2001-11       Impact factor: 4.942

4.  Evolutionary relationships and systematics of the alphaviruses.

Authors:  A M Powers; A C Brault; Y Shirako; E G Strauss; W Kang; J H Strauss; S C Weaver
Journal:  J Virol       Date:  2001-11       Impact factor: 5.103

5.  PE2 cleavage mutants of Sindbis virus: correlation between viral infectivity and pH-dependent membrane fusion activation of the spike heterodimer.

Authors:  J M Smit; W B Klimstra; K D Ryman; R Bittman; R E Johnston; J Wilschut
Journal:  J Virol       Date:  2001-11       Impact factor: 5.103

6.  Infectious enveloped RNA virus antigenic chimeras.

Authors:  S D London; A L Schmaljohn; J M Dalrymple; C M Rice
Journal:  Proc Natl Acad Sci U S A       Date:  1992-01-01       Impact factor: 11.205

7.  Changes of the secondary structure of the 5' end of the Sindbis virus genome inhibit virus growth in mosquito cells and lead to accumulation of adaptive mutations.

Authors:  Rafik Fayzulin; Ilya Frolov
Journal:  J Virol       Date:  2004-05       Impact factor: 5.103

8.  Sequence analysis of three Sindbis virus mutants temperature-sensitive in the capsid protein autoprotease.

Authors:  C S Hahn; E G Strauss; J H Strauss
Journal:  Proc Natl Acad Sci U S A       Date:  1985-07       Impact factor: 11.205

Review 9.  The alphaviruses: gene expression, replication, and evolution.

Authors:  J H Strauss; E G Strauss
Journal:  Microbiol Rev       Date:  1994-09

10.  Sindbis virus attachment: isolation and characterization of mutants with impaired binding to vertebrate cells.

Authors:  J Dubuisson; C M Rice
Journal:  J Virol       Date:  1993-06       Impact factor: 5.103
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.