Literature DB >> 191840

Cleavage of Rous sarcoma viral polypeptide precursor into internal structural proteins in vitro involves viral protein p15.

K von der Helm.   

Abstract

The polypeptide precursor pr76 to the internal viral group specific (gs) antigen proteins of Rous sarcoma virus, synthesized in a cell-free system of ascites cells, has been processed in vitro into the viral proteins by purified viral protein p15 as well as by disrupted Rous sarcoma virus. Disrupted Rauscher murine leukemia virus does not stimulate the cleavage process in vitro. Autocatalytic cleavage of the polypeptide precursor pr76 or Rous sarcoma virus, which contains the peptide sequence of p15, is not observed.

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Year:  1977        PMID： 191840      PMCID： PMC430528          DOI： 10.1073/pnas.74.3.911

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  23 in total

1.  Virus-specific precursor polypeptides in cells infected with Rauscher leukemia virus.

Authors:  D Zaanie; A L Gielkens; M J Dekker-michielsen; H P Bloemers
Journal:  Virology       Date:  1975-10       Impact factor: 3.616

2.  Translation of Rous sarcoma virus RNA in a cell-free system from ascites Krebs II cells.

Authors:  K von der Helm; P H Duesberg
Journal:  Proc Natl Acad Sci U S A       Date:  1975-02       Impact factor: 11.205

3.  Identification of a viral protein involved in post-translational maturation of the encephalomyocarditis virus capsid precursor.

Authors:  C Lawrence; R E Thach
Journal:  J Virol       Date:  1975-04       Impact factor: 5.103

4.  Generation of avian myeloblastosis virus structural proteins by proteolytic cleavage of a precursor polypeptide.

Authors:  V M Vogt; R Eisenman; H Diggelmann
Journal:  J Mol Biol       Date:  1975-08-15       Impact factor: 5.469

5.  Cell-free translation of virion RNA from nondefective and transformation-defective Rous sarcoma viruses.

Authors:  T Pawson; G S Martin; A E Smith
Journal:  J Virol       Date:  1976-09       Impact factor: 5.103

6.  A proposed nomenclature for the virion proteins of oncogenic RNA viruses.

Authors:  J T August; D P Bolognesi; E Fleissner; R V Gilden; R C Nowinski
Journal:  Virology       Date:  1974-08       Impact factor: 3.616

7.  Polypeptide cleavages in the formation of poliovirus proteins.

Authors:  M F Jacobson; D Baltimore
Journal:  Proc Natl Acad Sci U S A       Date:  1968-09       Impact factor: 11.205

8.  Evidence for large precursor proteins in poliovirus synthesis.

Authors:  D F Summers; J V Maizel
Journal:  Proc Natl Acad Sci U S A       Date:  1968-03       Impact factor: 11.205

9.  Specific cleavage of viral proteins as steps in the synthesis and maturation of enteroviruses.

Authors:  J J Holland; E D Kiehn
Journal:  Proc Natl Acad Sci U S A       Date:  1968-07       Impact factor: 11.205

10.  Structural studies of avian myeloblastosis virus: comparison of polypeptides in virion and core component by dodecyl sulfate-polyacrylamide gel electrophoresis.

Authors:  K Stromberg; N E Hurley; N L Davis; R R Rueckert; E Fleissner
Journal:  J Virol       Date:  1974-02       Impact factor: 5.103
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  61 in total

1.  Extracellular cleavage of the glycoprotein precursor of Rous sarcoma virus.

Authors:  R Klemenz; H Diggelmann
Journal:  J Virol       Date:  1979-01       Impact factor: 5.103

2.  Biochemical properties of p15-associated protease in an avian RNA tumor virus.

Authors:  K J Dittmar; K Moelling
Journal:  J Virol       Date:  1978-10       Impact factor: 5.103

3.  Mutational analysis of human immunodeficiency virus type 1 protease suggests functional homology with aspartic proteinases.

Authors:  D D Loeb; C A Hutchison; M H Edgell; W G Farmerie; R Swanstrom
Journal:  J Virol       Date:  1989-01       Impact factor: 5.103

4.  Properties of avian retrovirus particles defective in viral protease.

Authors:  L Stewart; G Schatz; V M Vogt
Journal:  J Virol       Date:  1990-10       Impact factor: 5.103

5.  Assembly and processing of avian retroviral gag polyproteins containing linked protease dimers.

Authors:  H Burstein; D Bizub; A M Skalka
Journal:  J Virol       Date:  1991-11       Impact factor: 5.103

Review 6.  Expression of virus-encoded proteinases: functional and structural similarities with cellular enzymes.

Authors:  W G Dougherty; B L Semler
Journal:  Microbiol Rev       Date:  1993-12

7.  A model for assembly of type-c oncornaviruses.

Authors:  D P Bolognesi; R C Montelaro; S J Sullivan
Journal:  Med Microbiol Immunol       Date:  1977       Impact factor: 3.402

8.  Conditional human immunodeficiency virus type 1 protease mutants show no role for the viral protease early in virus replication.

Authors:  A H Kaplan; M Manchester; T Smith; Y L Yang; R Swanstrom
Journal:  J Virol       Date:  1996-09       Impact factor: 5.103

9.  Retrovirus protease characterized as a dimeric aspartic proteinase.

Authors:  I Katoh; Y Ikawa; Y Yoshinaka
Journal:  J Virol       Date:  1989-05       Impact factor: 5.103

10.  Sequence analysis of three Sindbis virus mutants temperature-sensitive in the capsid protein autoprotease.

Authors:  C S Hahn; E G Strauss; J H Strauss
Journal:  Proc Natl Acad Sci U S A       Date:  1985-07       Impact factor: 11.205
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