Literature DB >> 206548

The 5'-terminal leader sequence of late 16 S mRNA from cells infected with simian virus 40.

P K Ghosh, V B Reddy, J Swinscoe, P V Choudary, P Lebowitz, S M Weissman.   

Abstract

The 16 S mRNA that directs the synthesis of VP1, the major structural protein of Simian virus 40 (SV40), is composed of a leader sequence of 203 nucleotides joined to a transcript that contains all the codons for VP1. The leader is transcribed from DNA between 0.723 and 0.762 map units while the VP1 coding transcript is copied from DNA from 0.94 to 0.17 map units. The leader sequence joins the transcript of the coding region at a position 42 nucleotides upstream from the initiator codon for VP1 by a 3':5'-phosphodiester linkage. Longer leader sequences also occur in a portion of SV40 late mRNA.

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Year:  1978        PMID： 206548

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  56 in total

1.  Identification and mapping of N6-methyladenosine containing sequences in simian virus 40 RNA.

Authors:  D Canaani; C Kahana; S Lavi; Y Groner
Journal:  Nucleic Acids Res       Date:  1979-06-25       Impact factor: 16.971

2.  Segments of simian virus 40 DNA spanning most of the leader sequence of the major late viral messenger RNA are dispensable.

Authors:  K N Subramanian
Journal:  Proc Natl Acad Sci U S A       Date:  1979-06       Impact factor: 11.205

3.  Heterogeneity of the 5' terminus of late mRNA induced by a viable simian virus 40 deletion mutant.

Authors:  G Haegeman; H van Heuverswyn; D Gheysen; W Fiers
Journal:  J Virol       Date:  1979-08       Impact factor: 5.103

4.  Selective degradation of newly synthesized nonmessenger simian virus 40 transcripts.

Authors:  N H Chiu; M F Radonovich; M M Thoren; N P Salzman
Journal:  J Virol       Date:  1978-11       Impact factor: 5.103

5.  Mutational alterations within the simian virus 40 leader segment generate altered 16S and 19S mRNA's.

Authors:  L P Villarreal; R T White; P Berg
Journal:  J Virol       Date:  1979-01       Impact factor: 5.103

6.  Nucleotide sequence of the BK virus DNA segment encoding small t antigen.

Authors:  R Dhar; I Seif; G Khoury
Journal:  Proc Natl Acad Sci U S A       Date:  1979-02       Impact factor: 11.205

7.  The Drosophila melanogaster actin 5C gene uses two transcription initiation sites and three polyadenylation sites to express multiple mRNA species.

Authors:  B J Bond; N Davidson
Journal:  Mol Cell Biol       Date:  1986-06       Impact factor: 4.272

8.  Specific transcription of a 15-kilodalton zene gene in HeLa cell extracts.

Authors:  R S Boston; B A Larkins
Journal:  Plant Mol Biol       Date:  1986-01       Impact factor: 4.076

9.  Sequences of the 5' portion of the human c-sis gene: characterization of the transcriptional promoter and regulation of expression of the protein product by 5' untranslated mRNA sequences.

Authors:  L Ratner; B Thielan; T Collins
Journal:  Nucleic Acids Res       Date:  1987-08-11       Impact factor: 16.971

10.  Simian virus 40 major late promoter: an upstream DNA sequence required for efficient in vitro transcription.

Authors:  J Brady; M Radonovich; M Thoren; G Das; N P Salzman
Journal:  Mol Cell Biol       Date:  1984-01       Impact factor: 4.272
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