Literature DB >> 6891194

Variation in age at death of dogs of different sexes and breeds.

R T Bronson.   

Abstract

A retrospective study of necropsy data for 2,002 dogs showed that the mean age at death of neutered dogs of both sexes exceeded that of intact dogs, but the differences were not significant. A wide variation in mean age at death of 56 breeds and cross breeds, 3.0 to 9.9 years, was found. This variation was not correlated with mean breed body weight. An attempt was made to explain the variability by finding diseases to which dogs of the short-lived breeds were particularly susceptible. This was not possible in general, since the samples of each breed were small and the total number of diseases from which they died so large. Dogs of long-lived breeds died of diseases appropriate to their age, particularly cancer, 39% of the sample. In the sample as a whole, cancer accounted for 20% of deaths at 5 years and increased to and remained between 40% and 50% from 10 to 16 years of age.

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Year:  1982        PMID: 6891194

Source DB:  PubMed          Journal:  Am J Vet Res        ISSN: 0002-9645            Impact factor:   1.156


  31 in total

1.  The MTAP-CDKN2A locus confers susceptibility to a naturally occurring canine cancer.

Authors:  Abigail L Shearin; Benoit Hedan; Edouard Cadieu; Suzanne A Erich; Emmett V Schmidt; Daniel L Faden; John Cullen; Jerome Abadie; Erika M Kwon; Andrea Gröne; Patrick Devauchelle; Maud Rimbault; Danielle M Karyadi; Mary Lynch; Francis Galibert; Matthew Breen; Gerard R Rutteman; Catherine André; Heidi G Parker; Elaine A Ostrander
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2012-05-23       Impact factor: 4.254

Review 2.  The Companion Dog as a Model for the Longevity Dividend.

Authors:  Kate E Creevy; Steven N Austad; Jessica M Hoffman; Dan G O'Neill; Daniel E L Promislow
Journal:  Cold Spring Harb Perspect Med       Date:  2016-01-04       Impact factor: 6.915

3.  Translating Nanomedicine to Comparative Oncology-the Case for Combining Zinc Oxide Nanomaterials with Nucleic Acid Therapeutic and Protein Delivery for Treating Metastatic Cancer.

Authors:  R K DeLong; Yi-Hsien Cheng; Paige Pearson; Zhoumeng Lin; Calli Coffee; Elza Neelima Mathew; Amanda Hoffman; Raelene M Wouda; Mary Lynn Higginbotham
Journal:  J Pharmacol Exp Ther       Date:  2019-04-30       Impact factor: 4.030

4.  Do Female Dogs Age Differently Than Male Dogs?

Authors:  Jessica M Hoffman; Dan G O'Neill; Kate E Creevy; Steven N Austad
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2018-01-16       Impact factor: 6.053

5.  Franklin H. Epstein Lecture. Both ends of the leash--the human links to good dogs with bad genes.

Authors:  Elaine A Ostrander
Journal:  N Engl J Med       Date:  2012-08-16       Impact factor: 91.245

Review 6.  Modeling opportunities in comparative oncology for drug development.

Authors:  Ira K Gordon; Chand Khanna
Journal:  ILAR J       Date:  2010

7.  Antigen profiling analysis of vaccinia virus injected canine tumors: oncolytic virus efficiency predicted by boolean models.

Authors:  Alexander Cecil; Ivaylo Gentschev; Marion Adelfinger; Ingo Nolte; Thomas Dandekar; Aladar A Szalay
Journal:  Bioengineered       Date:  2014 Sep-Oct       Impact factor: 3.269

8.  Homologous Mutation to Human BRAF V600E Is Common in Naturally Occurring Canine Bladder Cancer--Evidence for a Relevant Model System and Urine-Based Diagnostic Test.

Authors:  Brennan Decker; Heidi G Parker; Deepika Dhawan; Erika M Kwon; Eric Karlins; Brian W Davis; José A Ramos-Vara; Patty L Bonney; Elizabeth A McNiel; Deborah W Knapp; Elaine A Ostrander
Journal:  Mol Cancer Res       Date:  2015-03-12       Impact factor: 5.852

Review 9.  Domestic dogs and cancer research: a breed-based genomics approach.

Authors:  Brian W Davis; Elaine A Ostrander
Journal:  ILAR J       Date:  2014

10.  Exploring mechanisms of sex differences in longevity: lifetime ovary exposure and exceptional longevity in dogs.

Authors:  David J Waters; Seema S Kengeri; Beth Clever; Julie A Booth; Aimee H Maras; Deborah L Schlittler; Michael G Hayek
Journal:  Aging Cell       Date:  2009-09-02       Impact factor: 9.304

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