Literature DB >> 6879185

Morphine tolerance in genetically selected rats induced by chronically elevated saccharin intake.

I Lieblich, E Cohen, J R Ganchrow, E M Blass, F Bergmann.   

Abstract

Rats of line LC2-Hi that drank about 50 milliliters of a highly palatable saccharin solution daily for 28 consecutive days did not show morphine analgesia or an opioid form of stress-induced analgesia and were not responsive to naloxone. These findings support the idea that chronically elevated saccharin intake may cause increased release and utilization of endogenous opiates.

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Year:  1983        PMID： 6879185     DOI： 10.1126/science.6879185

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  13 in total

1.  Effect of the blockade of mu1-opioid and 5HT2A-serotonergic/alpha1-noradrenergic receptors on sweet-substance-induced analgesia.

Authors:  E C C Rebouças; E N Segato; R Kishi; R L Freitas; M Savoldi; S Morato; N C Coimbra
Journal:  Psychopharmacology (Berl)       Date:  2004-12-10       Impact factor: 4.530

2.  Voluntary exercise and sucrose consumption enhance cannabinoid CB1 receptor sensitivity in the striatum.

Authors:  Valentina De Chiara; Francesco Errico; Alessandra Musella; Silvia Rossi; Giorgia Mataluni; Lucia Sacchetti; Alberto Siracusano; Maura Castelli; Francesca Cavasinni; Giorgio Bernardi; Alessandro Usiello; Diego Centonze
Journal:  Neuropsychopharmacology       Date:  2010-01       Impact factor: 7.853

Review 3.  Heritable variation in food preferences and their contribution to obesity.

Authors:  D R Reed; A A Bachmanov; G K Beauchamp; M G Tordoff; R A Price
Journal:  Behav Genet       Date:  1997-07       Impact factor: 2.805

4.  Extended heroin access increases heroin choices over a potent nondrug alternative.

Authors:  Magalie Lenoir; Lauriane Cantin; Nathalie Vanhille; Fuschia Serre; Serge H Ahmed
Journal:  Neuropsychopharmacology       Date:  2013-01-15       Impact factor: 7.853

5.  Effect of non-sucrose sweet tasting solution on neonatal heel prick responses.

Authors:  L A Ramenghi; G C Griffith; C M Wood; M I Levene
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  1996-03       Impact factor: 5.747

6.  Biphasic effects of chronic saccharin intake on pain responses of healthy and diabetic rats of two genetically selected strains.

Authors:  F Bergmann; E Cohen; I Lieblich
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

7.  Sucrose consumption enhances the analgesic effects of cigarette smoking in male and female smokers.

Authors:  Robin B Kanarek; Catherine Carrington
Journal:  Psychopharmacology (Berl)       Date:  2004-01-14       Impact factor: 4.530

8.  Contributions of taste factors and gender to opioid preference in C57BL and DBA mice.

Authors:  M L Forgie; B L Beyerstein; B K Alexander
Journal:  Psychopharmacology (Berl)       Date:  1988       Impact factor: 4.530

9.  Effectiveness of sucrose analgesia in newborns undergoing painful medical procedures.

Authors:  Anna Taddio; Vibhuti Shah; Rebecca Hancock; Ryan W Smith; Derek Stephens; Eshetu Atenafu; Joseph Beyene; Gideon Koren; Bonnie Stevens; Joel Katz
Journal:  CMAJ       Date:  2008-07-01       Impact factor: 8.262

10.  The analgesic effect of sucrose in full term infants: a randomised controlled trial.

Authors:  N Haouari; C Wood; G Griffiths; M Levene
Journal:  BMJ       Date:  1995-06-10
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