Literature DB >> 6875279

Phenotypes of the fourth complement component (C4) in black Americans from the southeastern United States.

B Budowle, J M Roseman, R C Go, W Louv, B O Barger, R T Acton.   

Abstract

C4 is composed of two tightly linked genes (C4A and C4B) lying within the major histocompatibility complex of chromosome 6 that can be demonstrated by agarose gel electrophoresis. Seven alleles and five alleles at the C4A and C4B loci, respectively, were detected in 169 black individuals from the southeastern United States. Furthermore, the phenotypic frequencies of C4A6, C4A5, C4A4, C4B4, C4B3 and C4BQ0 were significantly different between black and white Americans.

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Year:  1983        PMID: 6875279     DOI: 10.1111/j.1744-313x.1983.tb00795.x

Source DB:  PubMed          Journal:  J Immunogenet        ISSN: 0305-1811


  3 in total

1.  Complotypes in individuals of African origin: frequencies and possible extended MHC haplotypes.

Authors:  P A Fraser; B Moore; R Stein; S Alosco; A H Johnson; D Marcus-Bagley; Z Awdeh; E J Yunis; C A Alper
Journal:  Immunogenetics       Date:  1990       Impact factor: 2.846

2.  A product of the C4B locus lacking hemolytic activity.

Authors:  K Suzuki; G J O'Neill; H Matsumoto
Journal:  Hum Genet       Date:  1986-06       Impact factor: 4.132

3.  The complement component C4 in black Americans with type 1 (insulin-dependent) diabetes mellitus.

Authors:  B Budowle; J M Roseman; R C Go; B O Barger; R T Acton
Journal:  Diabetologia       Date:  1984-02       Impact factor: 10.122

  3 in total

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