Literature DB >> 3522406

A product of the C4B locus lacking hemolytic activity.

K Suzuki, G J O'Neill, H Matsumoto.   

Abstract

An unusual C4B allotype, C4B 4I, was identified in a study of C4 polymorphism in Japanese. This variant was defined as C4B using a murine monoclonal antibody specific for the C4d region of C4B. Hemolytic assay, however, revealed that the C4 variant, C4 BI was hemolytically inactive in contrast to other well-defined C4B locus products.

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Year:  1986        PMID： 3522406     DOI： 10.1007/bf00291595

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  11 in total

1.  Two HLA-linked loci controlling the fourth component of human complement.

Authors:  G J O'Neill; S Y Yang; B Dupont
Journal:  Proc Natl Acad Sci U S A       Date:  1978-10       Impact factor: 11.205

2.  C4 polymorphism: use of a monoclonal antibody to distinguish C4A and C4B locus products.

Authors:  G J O'Neill
Journal:  Vox Sang       Date:  1984       Impact factor: 2.144

3.  A hemolytically inactive gene product of factor B.

Authors:  G Mauff; G Federmann; G Hauptmann
Journal:  Immunobiology       Date:  1980       Impact factor: 3.144

4.  Statement on the nomenclature of human C4 allotypes.

Authors:  G Mauff; C A Alper; Z Awdeh; J R Batchelor; J Bertrams; G Bruun-Petersen; R L Dawkins; P Démant; J Edwards; H Grosse-Wilde; G Hauptmann; P Klouda; L Lamm; E Mollenhauer; C Nerl; B Olaisen; G O'Neill; C Rittner; M H Roos; V Skanes; P Teisberg; L Wells
Journal:  Immunobiology       Date:  1983-03       Impact factor: 3.144

5.  A haemolytically non-active C4 gene product.

Authors:  P Teisberg; B Olaisen; R Nordhagen; E Thorsby; T Geddedahl
Journal:  Immunobiology       Date:  1980       Impact factor: 3.144

6.  Chido and Rodgers blood groups are distinct antigenic components of human complement C4.

Authors:  G J O'Neill; S Y Yang; J Tegoli; R Berger; B Dupont
Journal:  Nature       Date:  1978-06-22       Impact factor: 49.962

7.  Different HLA antigen associations for the functionally active and inactive products of the complement C4F1 allele.

Authors:  G J O'Neill; P Miniter; M S Pollack; B Dupont
Journal:  Hum Immunol       Date:  1980-07       Impact factor: 2.850

8.  Phenotypes of the fourth complement component (C4) in black Americans from the southeastern United States.

Authors:  B Budowle; J M Roseman; R C Go; W Louv; B O Barger; R T Acton
Journal:  J Immunogenet       Date:  1983-06

9.  A molecular basis for the two locus model of human complement component C4.

Authors:  M H Roos; E Mollenhauer; P Démant; C Rittner
Journal:  Nature       Date:  1982-08-26       Impact factor: 49.962

10.  Inherited structural polymorphism of the fourth component of human complement.

Authors:  Z L Awdeh; C A Alper
Journal:  Proc Natl Acad Sci U S A       Date:  1980-06       Impact factor: 11.205
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  1 in total

1.  The study of a French family with two duplicated C4A haplotypes.

Authors:  C M Giles; B Uring-Lambert; W Boksch; M Braun; J Goetz; R Neumann; G Mauff; G Hauptmann
Journal:  Hum Genet       Date:  1987-12       Impact factor: 4.132
  1 in total

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