Literature DB >> 6714536

The complement component C4 in black Americans with type 1 (insulin-dependent) diabetes mellitus.

B Budowle, J M Roseman, R C Go, B O Barger, R T Acton.   

Abstract

The complement component C4 variants C4A 4, C4B 4 and C4B Q0 were found to be significantly increased in 64 black patients with Type 1 (insulin-dependent) diabetes compared with 169 black control subjects, yielding relative risks of 3.3, 2.9 and 3.4, respectively. The increased frequencies of C4B 4 and C4B Q0 in black Type 1 diabetic patients are similar to those found in Caucasoid Type 1 diabetic patients. The data suggest that Type 1 diabetes in black Americans may be partially due to admixture of genes from whites.

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Year:  1984        PMID： 6714536     DOI： 10.1007/bf00281127

Source DB:  PubMed          Journal:  Diabetologia        ISSN： 0012-186X            Impact factor:   10.122


  23 in total

1.  On estimating the relation between blood group and disease.

Authors:  B WOOLF
Journal:  Ann Hum Genet       Date:  1955-06       Impact factor: 1.670

2.  Diabetes mellitus in the urbanized Johannesburg African.

Authors:  H C SEFTEL; E SCHULTZ
Journal:  S Afr Med J       Date:  1961-01-28

3.  Two HLA-linked loci controlling the fourth component of human complement.

Authors:  G J O'Neill; S Y Yang; B Dupont
Journal:  Proc Natl Acad Sci U S A       Date:  1978-10       Impact factor: 11.205

Review 4.  Activation of the complement system by antibody-antigen complexes: the classical pathway.

Authors:  R R Porter; K B Reid
Journal:  Adv Protein Chem       Date:  1979

5.  A haemolytically non-active C4 gene product.

Authors:  P Teisberg; B Olaisen; R Nordhagen; E Thorsby; T Geddedahl
Journal:  Immunobiology       Date:  1980       Impact factor: 3.144

6.  Type 1 diabetes and the HLA-D locus.

Authors:  J A Sachs; A G Cudworth; D Jaraquemada; A N Gorsuch; H Festenstein
Journal:  Diabetologia       Date:  1980-01       Impact factor: 10.122

7.  HLA-DR specificities among black Americans with juvenile-onset diabetes.

Authors:  G E Rodey; N White; T E Frazer; R J Duquesnoy; J V Santiago
Journal:  N Engl J Med       Date:  1979-10-11       Impact factor: 91.245

8.  Properdin factor B(Bf) allele BfF1 specifies an HLA-B18 diabetogenic haplotype.

Authors:  J Dornan; P Allan; E P Noel; B Larsen; N R Farid
Journal:  Diabetes       Date:  1980-06       Impact factor: 9.461

9.  HLA associations with insulin-dependent diabetes mellitus in a sample of the American Black population.

Authors:  P J Reitnauer; J M Roseman; B O Barger; C C Murphy; K A Kirk; R T Acton
Journal:  Tissue Antigens       Date:  1981-03

10.  The Pittsburgh insulin-dependent diabetes mellitus (IDDM) registry. The incidence of insulin-dependent diabetes mellitus in Allegheny County, Pennsylvania (1965-1976).

Authors:  R E LaPorte; H A Fishbein; A L Drash; L H Kuller; B B Schneider; T J Orchard; D K Wagener
Journal:  Diabetes       Date:  1981-04       Impact factor: 9.461
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  2 in total

1.  Complotypes in individuals of African origin: frequencies and possible extended MHC haplotypes.

Authors:  P A Fraser; B Moore; R Stein; S Alosco; A H Johnson; D Marcus-Bagley; Z Awdeh; E J Yunis; C A Alper
Journal:  Immunogenetics       Date:  1990       Impact factor: 2.846

2.  Genetic and Molecular Basis of QTL of Diabetes in Mouse: Genes and Polymorphisms.

Authors:  Peng Gao; Yan Jiao; Qing Xiong; Cong-Yi Wang; Ivan Gerling; Weikuan Gu
Journal:  Curr Genomics       Date:  2008       Impact factor: 2.236
  2 in total

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