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Literature DB >> 6819707

Distribution of lysozyme, alpha 1-Antichymotrypsin and alpha 1-Antitrypsin in adenocarcinomas of the stomach and large intestine. An immunohistochemical study.

C Kittas, K Aroni, L Kotsis, C S Papadimitriou.

Abstract

Lysozyme, alpha 1-Antichymotrypsin and alpha 1-Antitrypsin were demonstrated by an immunoperoxidase technique (PAP) in malignant cells of adenocarcinomas of the stomach but not of the large intestine. Lymph-node metastases showed identical immunoreactivity to that of the primary tumour. Neoplasms arising from the cardia, the body and the pyloric antrum of the stomach showed different immunostaining reactions. It seems that these differences partly reflect the distribution of lysozyme, alpha 1-Antichymotrypsin and alpha 1-Antitrypsin in the normal gastric mucosa. The usefulness of our findings in the identification of the primary tumour in cases of lymph node metastases of unknown origin, is also discussed.

Entities: Disease Gene

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Year: 1982 PMID： 6819707 DOI： 10.1007/bf00618865

Source DB: PubMed Journal: Virchows Arch A Pathol Anat Histopathol ISSN： 0174-7398

12 in total

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Journal: Virchows Arch A Pathol Anat Histopathol Date: 1984