Literature DB >> 6808963

Anaerobic degradation of uric acid via pyrimidine derivatives by selenium-starved cells of Clostridium purinolyticum.

P Dürre, J R Andreesen.   

Abstract

Clostridium purinolyticum decomposed uric acid via pyrimidine derivatives under selenium starvation conditions. Products were acetate, formate, glycine, ammonia, and CO2. 4,5-Diaminouracil could be identified as an intermediate after converting the labile substance into 6,7-dimethyllumazine. The breakdown of uric acid was inhibited by EDTA. High-pressure liquid chromatography methods have been developed for the simultaneous determination of uric acid, 4,5-diaminouracil, and 6,7-dimethyllumazine. The significance of the new pathway is discussed.

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Year:  1982        PMID： 6808963     DOI： 10.1007/BF00405889

Source DB:  PubMed          Journal:  Arch Microbiol        ISSN： 0302-8933            Impact factor:   2.552


  30 in total

1.  Reductive degradation of pyrimidines. I. The isolation and characterization of a uracil fermenting bacterium, Clostridium uracilicum nov. spec.

Authors:  L L CAMPBELL
Journal:  J Bacteriol       Date:  1957-02       Impact factor: 3.490

2.  Catabolism of purines in clostridium sticklandii [proceedings].

Authors:  R Schäfer; A C Schwartz
Journal:  Zentralbl Bakteriol Orig A       Date:  1976-08

3.  Clostridium acidi-uridi and Clostridium cylindrosporum, Organisms Fermenting Uric Acid and Some Other Purines.

Authors:  H A Barker; J V Beck
Journal:  J Bacteriol       Date:  1942-03       Impact factor: 3.490

4.  Separation and quantitation of purines and their anaerobic and aerobic degradation products by high-pressure liquid chromatography.

Authors:  P Dürre; J P Andreesen
Journal:  Anal Biochem       Date:  1982-06       Impact factor: 3.365

5.  Uric acid-induced decrease in rat insulin secretion.

Authors:  F W Scott; K D Trick; B Stavric; J T Braaten; Y Siddiqui
Journal:  Proc Soc Exp Biol Med       Date:  1981-01

6.  Biosynthesis of riboflavin: enzymatic conversion of 5-amino-2,4-dioxy-6-ribitylaminopyrimidine to 6,7-dimethyl-8-ribityllumazine.

Authors:  I J Hollander; J C Braman; G M Brown
Journal:  Biochem Biophys Res Commun       Date:  1980-05-30       Impact factor: 3.575

7.  New amino acids, and heterocyclic compounds participating in the Stickland reaction of Clostridium sticklandii.

Authors:  A C Schwartz; R Schäfer
Journal:  Arch Mikrobiol       Date:  1973-11-02

8.  The metabolism of pyrimidines by proteolytic clostridia.

Authors:  M G Hilton
Journal:  Arch Microbiol       Date:  1975       Impact factor: 2.552

9.  Degradation of pyrimidine bases in Clostridium sticklandii.

Authors:  R Schäfer; A C Schwartz
Journal:  Arch Microbiol       Date:  1980-01       Impact factor: 2.552

10.  Fermentation of fumarate and L-malate by Clostridium formicoaceticum.

Authors:  M Dorn; J R Andreesen; G Gottschalk
Journal:  J Bacteriol       Date:  1978-01       Impact factor: 3.490
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  4 in total

1.  Comparative studies on physiology and taxonomy of obligately purinolytic clostridia.

Authors:  H Schiefer-Ullrich; R Wagner; P Dürre; J R Andreesen
Journal:  Arch Microbiol       Date:  1984-08       Impact factor: 2.552

2.  Purine and glycine metabolism by purinolytic clostridia.

Authors:  P Dürre; J R Andreesen
Journal:  J Bacteriol       Date:  1983-04       Impact factor: 3.490

3.  Draft Genome Sequence of Purine-Degrading Gottschalkia purinilyticum (Formerly Clostridium purinilyticum) WA1 (DSM 1384).

Authors:  Anja Poehlein; Frank R Bengelsdorf; Bettina Schiel-Bengelsdorf; Rolf Daniel; Peter Dürre
Journal:  Genome Announc       Date:  2015-09-24

4.  Fecal transplant modifies urine chemistry risk factors for urinary stone disease.

Authors:  Joshua M Stern; Marcia Urban-Maldonado; Mykhaylo Usyk; Ignacio Granja; Daniel Schoenfeld; Kelvin P Davies; Ilir Agalliu; John Asplin; Robert Burk; Sylvia O Suadicani
Journal:  Physiol Rep       Date:  2019-02
  4 in total

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