Literature DB >> 678435

Formylhydrazine carcinogenesis in mice.

B Toth.   

Abstract

Administration of 0.125% formylhydrazine in drinking water to 6-week-old randomly bred Swiss albino mice for life, induced lung tumours. Compared to untreated controls, the lung-tumour incidence rose from 15 to 94% in the females and from 22 to 100% in the males. The treatment had no detectable tumorigenic effect in other organs.

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Year:  1978        PMID： 678435      PMCID： PMC2009651          DOI： 10.1038/bjc.1978.140

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  11 in total

1.  CARCINOGENESIS STUDY WITH DIMETHYLNITROSAMINE ADMINISTERED ORALLY TO ADULT AND SUBCUTANEOUSLY TO NEWBORN BALB-C MICE.

Authors:  B TOTH; P N MAGEE; P SHUBIK
Journal:  Cancer Res       Date:  1964-11       Impact factor: 12.701

Review 2.  Naturally occurring compounds Containing a nitrogen-nitrogen bond.

Authors:  T A LaRue
Journal:  Lloydia       Date:  1977 Jul-Aug

3.  1-Carbamyl-2-phenylhydrazine tumorigenesis in Swiss mice. Morphology of lung adenomas.

Authors:  B Toth; H Shimizu
Journal:  J Natl Cancer Inst       Date:  1974-01       Impact factor: 13.506

4.  1,1-Dimethylhydrazine (unsymmetrical) carcinogenesis in mice. Light microscopic and ultrastructural studies on neoplastic blood vessels.

Authors:  B Toth
Journal:  J Natl Cancer Inst       Date:  1973-01       Impact factor: 13.506

5.  Caffeine inhibition of postreplication repair of N-acetoxy-2-acetylamino fluorene-damaged DNA in Chinese hamster cells.

Authors:  J E Trosko; P Frank; E H Chu; J E Becker
Journal:  Cancer Res       Date:  1973-10       Impact factor: 12.701

6.  Hydrazine, methylhydrazine and methylhydrazine sulfate carcinogenesis in Swiss mice. Failure of ammonium hydroxide to interfere in the development of tumors.

Authors:  B Toth
Journal:  Int J Cancer       Date:  1972-01-15       Impact factor: 7.396

7.  [Gyromitrin, the poison of Gyromitra esculenta. 16. On the fungi contents].

Authors:  P H List; P Luft
Journal:  Arch Pharm Ber Dtsch Pharm Ges       Date:  1968-04

8.  Synthetic and naturally occurring hydrazines as possible cancer causative agents.

Authors:  B Toth
Journal:  Cancer Res       Date:  1975-12       Impact factor: 12.701

9.  Formation of methylhydrazine from acetaldehyde N-methyl-N-formylhydrazone, a component of Gyromitra esculenta.

Authors:  D Nagel; L Wallcave; B Toth; R Kupper
Journal:  Cancer Res       Date:  1977-09       Impact factor: 12.701

10.  Tumorigenic agents in unburned processed tobacco: N-nitrosodiethanolamine and 1,1-dimethylhydrazine.

Authors:  I Schmeltz; S Abidi; D Hoffmann
Journal:  Cancer Lett       Date:  1977-01       Impact factor: 8.679
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  6 in total

1.  Tumor induction with hexanal methylformylhydrazone of Gyromitra esculenta.

Authors:  B Toth; J Taylor; P Gannett
Journal:  Mycopathologia       Date:  1991-08       Impact factor: 2.574

2.  1,2-di-n-butylhydrazine dihydrochloride carcinogenesis in mice.

Authors:  B Toth; D Nagel
Journal:  Experientia       Date:  1981-07-15

3.  Lung tumorigenesis by 1,2-diformylhydrazine in mice.

Authors:  B Toth; J Erickson
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1978-08-24

4.  Carcinogenesis by pentanal methylformylhydrazone of Gyromitra esculenta in mice.

Authors:  B Toth; C R Raha
Journal:  Mycopathologia       Date:  1987-05       Impact factor: 2.574

5.  Actual new cancer-causing hydrazines, hydrazides, and hydrazones.

Authors:  B Toth
Journal:  J Cancer Res Clin Oncol       Date:  1980       Impact factor: 4.553

6.  A carcinogenic potency database of the standardized results of animal bioassays.

Authors:  L S Gold; C B Sawyer; R Magaw; G M Backman; M de Veciana; R Levinson; N K Hooper; W R Havender; L Bernstein; R Peto
Journal:  Environ Health Perspect       Date:  1984-12       Impact factor: 9.031
  6 in total

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