Literature DB >> 6773531

Gold does not alter the arthritic, humoral, or cellular responses in rats with type II collagen-induced arthritis.

W J McCune, D E Trentham, J R David.   

Abstract

We assessed the effects of administration of gold sodium thiomalate on the clinical and immunologic manifestations of type II collagen-induced arthritis in rats. Injections of varying doses of gold did not alter these parameters significantly. Thus, there was no evidence in this animal model that gold possesses either antiinflammatory or immunosuppressive properties.

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Year:  1980        PMID： 6773531     DOI： 10.1002/art.1780230809

Source DB:  PubMed          Journal:  Arthritis Rheum        ISSN： 0004-3591


  10 in total

1.  Bisphosphonates in collagen arthritis.

Authors:  H M Markusse; G J Lafeber; F C Breedveld
Journal:  Rheumatol Int       Date:  1990       Impact factor: 2.631

2.  Effects of gold sodium thiomalate, cyclosporin A, cyclophosphamide, and placebo on collagen-induced arthritis in rats.

Authors:  G W Cannon; S McCall; B C Cole; L A Radov; J R Ward; M M Griffiths
Journal:  Agents Actions       Date:  1993-03

3.  The influence of a peptide sequence from PF-4 (CT-112) on type II collagen-induced arthritis in mice.

Authors:  P H Wooley; J D Whalen; J A Dutcher; D F Counts
Journal:  Inflamm Res       Date:  1995-08       Impact factor: 4.575

4.  The effects of mesoporphyrin on experimental arthritis in mice.

Authors:  H Nagai; Y Takaoka; H Mori; N Matsuura
Journal:  Inflamm Res       Date:  1996-06       Impact factor: 4.575

5.  Effect of gold salts, D-penicillamine and benoxaprofen on type II collagen-induced arthritis in rats.

Authors:  A J Lewis; R P Carlson; J Chang; F DeLustro
Journal:  Agents Actions       Date:  1984-06

6.  Effects of various anti-inflammatory drugs on type II collagen-induced arthritis in rats.

Authors:  K Phadke; J Carroll; S Nanda
Journal:  Clin Exp Immunol       Date:  1982-03       Impact factor: 4.330

7.  Assessment of drugs for activity in established type II collagen arthritis.

Authors:  S A Jones; A J Kennedy; N A Roberts
Journal:  Agents Actions       Date:  1982-12

8.  Failure of calcitonin to inhibit collagen-induced arthritis in rats.

Authors:  J M Stuart; P R Bandy; R S Pinals; A S Townes
Journal:  Agents Actions       Date:  1982-12

Review 9.  Conditional pharmacology/toxicology V: ambivalent effects of thiocyanate upon the development and the inhibition of experimental arthritis in rats by aurothiomalate (Myocrysin®) and metallic silver.

Authors:  Michael Whitehouse; Desley Butters; Barrie Vernon-Roberts
Journal:  Inflammopharmacology       Date:  2013-05-19       Impact factor: 4.473

10.  Collagen, autoimmunity and disease.

Authors:  A J Kennedy
Journal:  J R Soc Med       Date:  1981-09       Impact factor: 18.000
  10 in total

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