Literature DB >> 2315608

Bisphosphonates in collagen arthritis.

H M Markusse1, G J Lafeber, F C Breedveld.   

Abstract

Bisphosphonates suppress bone destruction in various diseases. We studied the effects of 3-amino-hydroxypropylidene-1,1-bisphosphonate (APD), and dimethyl-APD in the collagen model of chronic arthritis in rats. The incidence and severity of arthritis was not lower in rats treated with APD or dimethyl-APD compared with controls. The cellular and humoral immune responses to collagen were also similar in the treated and untreated animals. In all animal groups the same bone destruction was found radiographically 42 days after immunization. This study demonstrates that bisphosphonates do not suppress the course of collagen arthritis in rats.

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Year:  1990        PMID： 2315608     DOI： 10.1007/bf00541325

Source DB:  PubMed          Journal:  Rheumatol Int        ISSN： 0172-8172            Impact factor:   2.631


  13 in total

1.  Studies on the chronic phase of adjuvant arthritis: effect of SR 41319, a new diphosphonate.

Authors:  A Barbier; J C Breliére; B Remandet; R Roncucci
Journal:  Ann Rheum Dis       Date:  1986-01       Impact factor: 19.103

2.  Radiologic analysis of arthritis in rats after systemic injection of streptococcal cell walls.

Authors:  R L Clark; J T Cuttino; S K Anderle; W J Cromartie; J H Schwab
Journal:  Arthritis Rheum       Date:  1979-01

3.  Treatment of Paget's disease with (3-amino-1-hydroxypropylidene)-1, 1-bisphosphonate (A.P.D.).

Authors:  W B Frijlink; O L Bijvoet; J te Velde; G Heynen
Journal:  Lancet       Date:  1979-04-14       Impact factor: 79.321

Review 4.  Progress in the understanding of inducible models of chronic arthritis.

Authors:  F C Breedveld; D E Trentham
Journal:  Rheum Dis Clin North Am       Date:  1987-12       Impact factor: 2.670

5.  Comparison of aminohydroxypropylidene diphosphonate, mithramycin, and corticosteroids/calcitonin in treatment of cancer-associated hypercalcaemia.

Authors:  S H Ralston; M D Gardner; F J Dryburgh; A S Jenkins; R A Cowan; I T Boyle
Journal:  Lancet       Date:  1985-10-26       Impact factor: 79.321

6.  Effect of psychological stress on the induction of arthritis in rats.

Authors:  M P Rogers; D E Trentham; W J McCune; B I Ginsberg; H G Rennke; P Reich; J R David
Journal:  Arthritis Rheum       Date:  1980-12

7.  Immunosuppression by fractionated total lymphoid irradiation in collagen arthritis.

Authors:  W J McCune; J A Buckley; J A Belli; D E Trentham
Journal:  Arthritis Rheum       Date:  1982-05

8.  Autoimmunity to collagen in adjuvant arthritis of rats.

Authors:  D E Trentham; W J McCune; P Susman; J R David
Journal:  J Clin Invest       Date:  1980-11       Impact factor: 14.808

9.  Collagen-induced arthritis in the rat: modification of immune and arthritic responses by free collagen and immune anti-collagen antiserum.

Authors:  N A Staines; T Hardingham; M Smith; B Henderson
Journal:  Immunology       Date:  1981-12       Impact factor: 7.397

10.  Prevention of steroid-induced osteoporosis with (3-amino-1-hydroxypropylidene)-1,1-bisphosphonate (APD).

Authors:  I R Reid; A R King; C J Alexander; H K Ibbertson
Journal:  Lancet       Date:  1988-01-23       Impact factor: 79.321
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  4 in total

1.  Contrast between effects of aminobisphosphonates and non-aminobisphosphonates on collagen-induced arthritis in mice.

Authors:  M Nakamura; T Ando; M Abe; K Kumagai; Y Endo
Journal:  Br J Pharmacol       Date:  1996-09       Impact factor: 8.739

2.  Incadronate disodium inhibits joint destruction and periarticular bone loss only in the early phase of rat adjuvant-induced arthritis.

Authors:  Tomoyuki Akiyama; Satoshi Mori; Tasuku Mashiba; Kensaku Miyamoto; Satoshi Komatsubara; Yongping Cao; Takeshi Manabe; Hiromichi Norimatsu; Hiroaki Dobashi; Michiaki Tokuda
Journal:  J Bone Miner Metab       Date:  2005       Impact factor: 2.626

3.  Effects of clodronate and alendronate on local and systemic changes in bone metabolism in rats with adjuvant arthritis.

Authors:  Fumiaki Itoh; Shigemi Aoyagi; Hiroshi Kusama; Masami Kojima; Hiroshi Kogo
Journal:  Inflammation       Date:  2004-02       Impact factor: 4.092

4.  Effect of clodronate on established collagen-induced arthritis in rats.

Authors:  T Osterman; K Kippo; L Laurén; R Hannuniemi; R Sellman
Journal:  Inflamm Res       Date:  1995-06       Impact factor: 4.575
  4 in total

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