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39 in total

1. Evidence for involvement of polymorphic CYP2C19 and 2C9 in the N-demethylation of sertraline in human liver microsomes.

Authors: Z H Xu; W Wang; X J Zhao; S L Huang; B Zhu; N He; Y Shu; Z Q Liu; H H Zhou
Journal: Br J Clin Pharmacol Date: 1999-09 Impact factor: 4.335

2. Inter-individual variability in levels of human microsomal protein and hepatocellularity per gram of liver.

Authors: Z E Wilson; A Rostami-Hodjegan; J L Burn; A Tooley; J Boyle; S W Ellis; G T Tucker
Journal: Br J Clin Pharmacol Date: 2003-10 Impact factor: 4.335

3. Inhibition of CYP3A4 and CYP3A5 catalyzed metabolism of alprazolam and quinine by ketoconazole as racemate and four different enantiomers.

Authors: Annika Allqvist; Jun Miura; Leif Bertilsson; Rajaa A Mirghani
Journal: Eur J Clin Pharmacol Date: 2007-01-03 Impact factor: 2.953

4. The effect of age on glucuronidation and sulphation of paracetamol by human liver fractions.

Authors: B Herd; H Wynne; P Wright; O James; K Woodhouse
Journal: Br J Clin Pharmacol Date: 1991-12 Impact factor: 4.335

5. Role of human liver microsomal CYP2C9 in the biotransformation of lornoxicam.

Authors: P Bonnabry; T Leemann; P Dayer
Journal: Eur J Clin Pharmacol Date: 1996 Impact factor: 2.953

6. The trans-stilbene oxide-active glutathione transferase in human mononuclear leucocytes is identical with the hepatic glutathione transferase mu.

Authors: J Seidegård; C Guthenberg; R W Pero; B Mannervik
Journal: Biochem J Date: 1987-09-15 Impact factor: 3.857

Drug metabolism in human liver in vitro: establishment of a human liver bank.

1. Evidence for involvement of polymorphic CYP2C19 and 2C9 in the N-demethylation of sertraline in human liver microsomes.

2. Inter-individual variability in levels of human microsomal protein and hepatocellularity per gram of liver.

3. Inhibition of CYP3A4 and CYP3A5 catalyzed metabolism of alprazolam and quinine by ketoconazole as racemate and four different enantiomers.

4. The effect of age on glucuronidation and sulphation of paracetamol by human liver fractions.

5. Role of human liver microsomal CYP2C9 in the biotransformation of lornoxicam.

6. The trans-stilbene oxide-active glutathione transferase in human mononuclear leucocytes is identical with the hepatic glutathione transferase mu.

7. Determination of a human hepatic microsomal scaling factor for predicting in vivo drug clearance.

8. Coumarin 7-hydroxylase activity in human liver microsomes. Properties of the enzyme and interspecies comparisons.

9. Carbamazepine metabolism in man. Induction and pharmacogenetic aspects.

10. Identification of cytochromes P450 2C9 and 3A4 as the major catalysts of phenprocoumon hydroxylation in vitro.