Literature DB >> 3689332

The trans-stilbene oxide-active glutathione transferase in human mononuclear leucocytes is identical with the hepatic glutathione transferase mu.

J Seidegård1, C Guthenberg, R W Pero, B Mannervik.   

Abstract

A glutathione transferase from human mononuclear leucocytes with high activity towards trans-stilbene oxide (GT-tSBO) was purified. GT-tSBO is expressed in only about 50% of the individuals studied. As judged from activity measurements, immunological studies and the fact that only those individuals who express glutathione transferase mu have high activity towards trans-stilbene oxide, it is concluded that the hepatic transferase mu is identical with the glutathione transferase (GT-tSBO) in mononuclear leucocytes.

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Year:  1987        PMID： 3689332      PMCID： PMC1148346          DOI： 10.1042/bj2460783

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  16 in total

1.  Glutathione S-transferases. The first enzymatic step in mercapturic acid formation.

Authors:  W H Habig; M J Pabst; W B Jakoby
Journal:  J Biol Chem       Date:  1974-11-25       Impact factor: 5.157

2.  Purification of a new glutathione S-transferase (transferase mu) from human liver having high activity with benzo(alpha)pyrene-4,5-oxide.

Authors:  M Warholm; C Guthenberg; B Mannervik; C von Bahr
Journal:  Biochem Biophys Res Commun       Date:  1981-01-30       Impact factor: 3.575

3.  Biochemical genetics of glutathione-S-transferase in man.

Authors:  P G Board
Journal:  Am J Hum Genet       Date:  1981-01       Impact factor: 11.025

4.  Molecular and catalytic properties of glutathione transferase mu from human liver: an enzyme efficiently conjugating epoxides.

Authors:  M Warholm; C Guthenberg; B Mannervik
Journal:  Biochemistry       Date:  1983-07-19       Impact factor: 3.162

5.  "Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A.

Authors:  W N Burnette
Journal:  Anal Biochem       Date:  1981-04       Impact factor: 3.365

6.  Glutathione transferase (human placenta).

Authors:  B Mannervik; C Guthenberg
Journal:  Methods Enzymol       Date:  1981       Impact factor: 1.600

7.  Identification of a new glutathione S-transferase in human liver.

Authors:  M Warholm; C Guthenberg; B Mannervik; C von Bahr; H Glaumann
Journal:  Acta Chem Scand B       Date:  1980

8.  Radiometric assays for mammalian epoxide hydrolases and glutathione S-transferase.

Authors:  S S Gill; K Ota; B D Hammock
Journal:  Anal Biochem       Date:  1983-05       Impact factor: 3.365

9.  The human glutathione S-transferases: studies on the tissue distribution and genetic variation of the GST1, GST2 and GST3 isozymes.

Authors:  R C Strange; C G Faulder; B A Davis; R Hume; J A Brown; W Cotton; D A Hopkinson
Journal:  Ann Hum Genet       Date:  1984-01       Impact factor: 1.670

10.  A glutathione transferase in human leukocytes as a marker for the susceptibility to lung cancer.

Authors:  J Seidegård; R W Pero; D G Miller; E J Beattie
Journal:  Carcinogenesis       Date:  1986-05       Impact factor: 4.944
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  13 in total

1.  Cloning, expression, and characterization of a class-mu glutathione transferase from human muscle, the product of the GST4 locus.

Authors:  W R Vorachek; W R Pearson; G S Rule
Journal:  Proc Natl Acad Sci U S A       Date:  1991-05-15       Impact factor: 11.205

2.  Human glutathione transferase A4-4: an alpha class enzyme with high catalytic efficiency in the conjugation of 4-hydroxynonenal and other genotoxic products of lipid peroxidation.

Authors:  I Hubatsch; M Ridderström; B Mannervik
Journal:  Biochem J       Date:  1998-02-15       Impact factor: 3.857

3.  Polymorphisms of CYP1A1, GSTM1 and GSTT1 Loci as the Genetic Predispositions of Oral Cancers and Other Oral Pathologies: Tobacco and Alcohol as Risk Modifiers.

Authors:  Sumana Chatterjee; Soujatya Dhar; Bani Sengupta; Ashish Ghosh; Manas De; Sumit Roy; Sila Chakrabarti
Journal:  Indian J Clin Biochem       Date:  2010-08-25

4.  Genetic deficiency of human class mu glutathione S-transferase isoenzymes in relation to the urinary excretion of the mercapturic acids of Z- and E-1,3-dichloropropene.

Authors:  R M Vos; R T van Welie; W H Peters; C T Evelo; J J Boogaards; N P Vermeulen; P J van Bladeren
Journal:  Arch Toxicol       Date:  1991       Impact factor: 5.153

5.  Identification of the trans-stilbene oxide-active glutathione transferase in human mononuclear leukocytes and in liver as GST1.

Authors:  J Seidegård; R W Pero; B Stille
Journal:  Biochem Genet       Date:  1989-04       Impact factor: 1.890

6.  Hereditary differences in the expression of the human glutathione transferase active on trans-stilbene oxide are due to a gene deletion.

Authors:  J Seidegård; W R Vorachek; R W Pero; W R Pearson
Journal:  Proc Natl Acad Sci U S A       Date:  1988-10       Impact factor: 11.205

7.  Identification of class-mu glutathione transferase genes GSTM1-GSTM5 on human chromosome 1p13.

Authors:  W R Pearson; W R Vorachek; S J Xu; R Berger; I Hart; D Vannais; D Patterson
Journal:  Am J Hum Genet       Date:  1993-07       Impact factor: 11.025

8.  Genotoxic risk for humans due to work place exposure to ethylene oxide: remarkable individual differences in susceptibility.

Authors:  J Fuchs; U Wullenweber; J G Hengstler; H G Bienfait; G Hiltl; F Oesch
Journal:  Arch Toxicol       Date:  1994       Impact factor: 5.153

9.  Purification and characterization of a new glutathione S-transferase, class theta, from human erythrocytes.

Authors:  K R Schröder; E Hallier; D J Meyer; F A Wiebel; A M Müller; H M Bolt
Journal:  Arch Toxicol       Date:  1996       Impact factor: 5.153

10.  Human intestinal glutathione S-transferases.

Authors:  W H Peters; H M Roelofs; F M Nagengast; J H van Tongeren
Journal:  Biochem J       Date:  1989-01-15       Impact factor: 3.857
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