Literature DB >> 6757760

Characterization of a regulatory region upstream of the ADR2 locus of S. cerevisiae.

D R Beier, E T Young.   

Abstract

We have used in vitro mutagenesis to identify a DNA sequence that is required for glucose regulation of the ADR2 locus of Saccharomyces cerevisiae. This region, located between 200 and 1,000 base pairs upstream of the structural gene for ADH II, has been identified by genetic and biochemical analysis as the site of ADR3, a cis-acting regulatory locus. If this region is deleted, ADR2 is no longer repressed by glucose. Moreover, if the sequence is excised and ligated in front of the ADC1 gene, it puts that gene under glucose control.

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Year:  1982        PMID： 6757760     DOI： 10.1038/300724a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  40 in total

1.  Hyperacetylation of chromatin at the ADH2 promoter allows Adr1 to bind in repressed conditions.

Authors:  Loredana Verdone; Jiansheng Wu; Kristen van Riper; Nataly Kacherovsky; Maria Vogelauer; Elton T Young; Michael Grunstein; Ernesto Di Mauro; Micaela Caserta
Journal:  EMBO J       Date:  2002-03-01       Impact factor: 11.598

2.  Identification and characterization of three genes that affect expression of ADH2 in Saccharomyces cerevisiae.

Authors:  L Karnitz; M Morrison; E T Young
Journal:  Genetics       Date:  1992-10       Impact factor: 4.562

3.  Adjacent upstream activation sequence elements synergistically regulate transcription of ADH2 in Saccharomyces cerevisiae.

Authors:  J Yu; M S Donoviel; E T Young
Journal:  Mol Cell Biol       Date:  1989-01       Impact factor: 4.272

4.  The construction of a stable starch-fermenting yeast strain using genetic engineering and rare-mating.

Authors:  T G Kim; K Kim
Journal:  Appl Biochem Biotechnol       Date:  1996-04       Impact factor: 2.926

5.  Isolation of the catalase A gene of Saccharomyces cerevisiae by complementation of the cta1 mutation.

Authors:  G Cohen; F Fessl; A Traczyk; J Rytka; H Ruis
Journal:  Mol Gen Genet       Date:  1985

6.  Expression of the Butyrivibrio fibrisolvens endo-beta-1,4-glucanase gene together with the Erwinia pectate lyase and polygalacturonase genes in Saccharomyces cerevisiae.

Authors:  P van Rensburg; W H van Zyl; I S Pretorius
Journal:  Curr Genet       Date:  1994-12       Impact factor: 3.886

7.  In vitro generation of specific deletions in DNA cloned in M13 vectors using synthetic oligodeoxyribonucleotides: mutants in the 5'-flanking region of the yeast alcohol dehydrogenase II gene.

Authors:  V L Chan; M Smith
Journal:  Nucleic Acids Res       Date:  1984-03-12       Impact factor: 16.971

8.  Carbon source dependence of transposable element-associated gene activation in Saccharomyces cerevisiae.

Authors:  A K Taguchi; M Ciriacy; E T Young
Journal:  Mol Cell Biol       Date:  1984-01       Impact factor: 4.272

9.  DNA sequence analysis of crown gall tumor T-DNA encoding the 0.7 kb transcript.

Authors:  J C McPherson
Journal:  Nucleic Acids Res       Date:  1984-03-12       Impact factor: 16.971

10.  ADH2 expression is repressed by REG1 independently of mutations that alter the phosphorylation of the yeast transcription factor ADR1.

Authors:  K M Dombek; S Camier; E T Young
Journal:  Mol Cell Biol       Date:  1993-07       Impact factor: 4.272
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