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Literature DB >> 673858

RNA methylation in vaccinia virus-infected chick embryo fibroblasts treated with homologous interferon.

H Kroath, H J Gross, C Jungwirth, G Bodo.

Abstract

Interferon-pretreatment of vaccinia-infected chick embryo fibroblasts resulted in a greater than 50% decrease in ribose methylation of the penultimate "cap" nucleotide in virus-specific mRNA. However, in contrast to results obtained with cell-free systems, in intact infected cells there was (a) no detectable reduction in methylation of the 5'-ultimate m7G of viral mRNA; (b) a virus specificity of the interferon-induced change in mRNA "CAP"-methylation seems unlikely and (c) analysis of the ribosomal and transfer RNA fractions isolated from interferon-treated and control cells revealed identical patterns of methylated nucleotides. Thus, the interferon-induced change in methylation is specific for mRNA "CAPS".

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Year: 1978 PMID： 673858 PMCID： PMC342175 DOI： 10.1093/nar/5.7.2441

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

26 in total

1. Inhibition of reovirus messenger RNA methylation in extracts of interferon-treated Ehrlich ascites tumor cells.

Authors: G C Sen; B Lebleu; G E Brown; M A Rebello; Y Furuichi; M Morgan; A J Shatkin; P Lengyel
Journal: Biochem Biophys Res Commun Date: 1975-07-08 Impact factor: 3.575

2. Methylation of cytoplasmic adenovirus RNA synthesized early and late in productive infection.

Authors: S M Fernandez; H J Raskas
Journal: Biochem Biophys Res Commun Date: 1975-09-02 Impact factor: 3.575

3. The purification fo four strains of poxvirus.

Authors: W K JOKLIK
Journal: Virology Date: 1962-09 Impact factor: 3.616

4. Blocks in elongation and initiation of protein synthesis induced by interferon treatment in mouse L cells.

Authors: J Content; B Lebleu; U Nudel; A Zilberstein; H Berissi; M Revel
Journal: Eur J Biochem Date: 1975-05

5. 5'-Terminal and internal methylated nucleotide sequences in HeLa cell mRNA.

Authors: C M Wei; A Gershowitz; B Moss
Journal: Biochemistry Date: 1976-01-27 Impact factor: 3.162

6. Characterization of Novikoff hepatoma mRNA methylation and heterogeneity in the methylated 5' terminus.

Authors: R C Desrosiers; K H Friderici; F M Rottman
Journal: Biochemistry Date: 1975-10-07 Impact factor: 3.162

7. Methyl labeling of HeLa cell hnRNA: a comparison with mRNA.

Authors: M Salditt-Georgieff; W Jelinek; J E Darnell; Y Furuichi; M Morgan; A Shatkin
Journal: Cell Date: 1976-02 Impact factor: 41.582

8. Acrylamide gel electrophoresis of HeLa cell nucleolar RNA.

Authors: R A Weinberg; U Loening; M Willems; S Penman
Journal: Proc Natl Acad Sci U S A Date: 1967-09 Impact factor: 11.205

9. Methyl-deficient mammalian transfer RNA: II. Homologous methylation in vitro of liver tRNA from normal and ethionine-fed rats: ethionine effect on 5-methyl-cytidine synthesis in vivo.

Authors: P Jank; H J Gross
Journal: Nucleic Acids Res Date: 1974-10 Impact factor: 16.971

4. Enhanced therapeutic efficacy of poly(ICLC) and ribavirin combinations against Rift Valley fever virus infection in mice.

Authors: M Kende; H W Lupton; W L Rill; H B Levy; P G Canonico
Journal: Antimicrob Agents Chemother Date: 1987-07 Impact factor: 5.191

4 in total