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Literature DB >> 446645

Altered or increased transfer-RNA methylation in the course of Interferon action on cells in culture?

Abstract

The induction of the antiviral state by Interferon might reflect the decrease of the rate of biosynthesis, the degradation or the alteration of one or several tRNAs. This could result in rate-limiting concentrations for codons common in viral RNA but rare in host mRNA. Altered methylation of tRNA could be the basis of such a phenomenon. However, we could not find an altered extent of methylation of total tRNA or an altered pattern of methylation, if mixed tRNAs were chromatographed on MAK- or BD-cellulose columns, despite a large range of conditions of pretreatment of chick embryo fibroblast cultures with interferon.

Entities: Gene Species

Mesh：

Substances：
Interferons
RNA, Transfer

Year: 1979 PMID： 446645 DOI： 10.1007/bf01960327

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

21 in total

1. Fractionation of amino acyl-acceptor RNA on a methylated albumin column.

Authors: N SUEOKA; T YAMANE
Journal: Proc Natl Acad Sci U S A Date: 1962-08 Impact factor: 11.205

2. Studies on vaccinia virus plaque formation and its inhibition by interferon. III. A simplified plaque inhibition assay of interferon.

Authors: J LINDENMANN; G E GIFFORD
Journal: Virology Date: 1963-03 Impact factor: 3.616

3. The inhibition of translation of synthetic polyribonucleotides and mengo RNA in extracts from interferon-treated L cells and its reversion by yeast tRNAs.

Authors: R Falcoff; B Lebleu; J Sanceau; J Weissenbach; G Dirheimer; J P Ebel; E Falcoff
Journal: Biochem Biophys Res Commun Date: 1976-02-23 Impact factor: 3.575

Review 4. The molecular mechanism of interferon action.

Authors: J A Lewis; E Falcoff; R Falcoff
Journal: Pathol Biol (Paris) Date: 1977-01

5. Functional adaptation of tRNA population.

Authors: J P Garel
Journal: J Theor Biol Date: 1974-01 Impact factor: 2.691

6. Mechanism of the interferon-induced block of mRNA translation in mouse L cells: reversal of the block by transfer RNA.

Authors: J Content; B Lebleu; A Zilberstein; H Berissi; M Revel
Journal: FEBS Lett Date: 1974-04-15 Impact factor: 4.124

7. Release of the inhibition of messenger RNA translation in extracts of interferon-treated Ehrlich ascites tumor cells by added transfer RNA.

Authors: S L Gupta; M L Sopori; P Lengyel
Journal: Biochem Biophys Res Commun Date: 1974-04-08 Impact factor: 3.575

8. Studies on the mechanism of interferon action: characterization of polysome-associated cellular RNAs modified by interferon.

Authors: F L Riley; H B Levy
Journal: Virology Date: 1977-01 Impact factor: 3.616