Literature DB >> 673849

DNA polymerases alpha beta and gamma in inherited diseases affecting DNA repair.

U Bertazzoni, A I Scovassi, M Stefanini, E Giulotto, S Spadari, A M Pedrini.   

Abstract

Fibroblasts derived from patients with diseases affecting DNA repair processes, such as Xeroderma Pigmentosum (classical and variant), Fanconi's anemia, Bloom's syndrome, Ataxia Telangiectasica, Progeria and Werner's syndrome, were assayed for the three DNA polymerases. The specific activities of these enzymes were found within the limits observed in normal human fibroblasts. Also the sedimentation properties of the three polymerases were unaltered.

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Year:  1978        PMID： 673849      PMCID： PMC342152          DOI： 10.1093/nar/5.6.2189

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  25 in total

1.  DNA polymerase of mitochondria is a gamma-polymerase.

Authors:  A Bolden; G P Noy; A Weissbach
Journal:  J Biol Chem       Date:  1977-05-25       Impact factor: 5.157

2.  Levels of DNA polymerases alpha, beta, and gamma in control and repair-deficient human diploid fibroblasts 1.

Authors:  V P Parker; M W Lieberman
Journal:  Nucleic Acids Res       Date:  1977-06       Impact factor: 16.971

Review 3.  DNA repair and human disease.

Authors:  B Lambert; U Ringborg
Journal:  Acta Med Scand       Date:  1976

4.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

5.  HeLa cell DNA polymerase gamma: further purification and properties of the enzyme.

Authors:  K W Knopf; M Yamada; A Weissbach
Journal:  Biochemistry       Date:  1976-10-05       Impact factor: 3.162

6.  Bloom's syndrome: DNA replication in cultured fibroblasts and lymphocytes.

Authors:  R Hand; J German
Journal:  Hum Genet       Date:  1977-10-14       Impact factor: 4.132

7.  Decreased repair of gamma ray damaged DNA in progeria.

Authors:  A J Rainbow; M Howes
Journal:  Biochem Biophys Res Commun       Date:  1977-01-24       Impact factor: 3.575

8.  Ultraviolet light sensitivity and delayed DNA-chain maturation in Bloom's syndrome fibroblasts.

Authors:  F Gianneli; P F Benson; S A Pawsey; P E Polani
Journal:  Nature       Date:  1977-02-03       Impact factor: 49.962

9.  Levels of DNA polymerase-alpha and beta in normal and xeroderma pigmentosum fibroblasts.

Authors:  U Bertazzoni; M Stefanini; G Pedrali-Noy; F Nuzzo; A Falaschi
Journal:  Nucleic Acids Res       Date:  1977-01       Impact factor: 16.971

10.  Chick-embryo DNA polymerase gamma. Identity of gamma-polymerases purified from nuclei and mitochondria.

Authors:  U Bertazzoni; A I Scovassi; G M Brun
Journal:  Eur J Biochem       Date:  1977-12-01
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  5 in total

Review 1.  Genetic and biochemical studies with ataxia telangiectasia. A review.

Authors:  P C Huang; R B Sheridan
Journal:  Hum Genet       Date:  1981       Impact factor: 4.132

2.  DNA polymerase alpha, beta and gamma activities in ultraviolet irradiated CV-1 monkey cells.

Authors:  R Wicker; A I Scovassi; S Nocentini
Journal:  Nucleic Acids Res       Date:  1979-04       Impact factor: 16.971

3.  Altered cellular response to UV irradiation in a patient affected by premature ageing.

Authors:  M Stefanini; G Orecchia; G Rabbiosi; F Nuzzo
Journal:  Hum Genet       Date:  1986-07       Impact factor: 4.132

4.  DNA ligase activity in human cell lines from normal donors and Bloom's syndrome patients.

Authors:  M Mezzina; J Nardelli; S Nocentini; G Remault; A Sarasin
Journal:  Nucleic Acids Res       Date:  1989-04-25       Impact factor: 16.971

Review 5.  Ataxia-telangiectasia: an inherited disorder of ionizing-radiation sensitivity in man. Progress in the elucidation of the underlying biochemical defect.

Authors:  P J McKinnon
Journal:  Hum Genet       Date:  1987-03       Impact factor: 4.132
  5 in total

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