Literature DB >> 6733565

Methylation of the O6 position of guanine in DNA is the most likely initiating event in carcinogenesis by methylating agents.

A E Pegg.   

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Year:  1984        PMID: 6733565     DOI: 10.3109/07357908409104376

Source DB:  PubMed          Journal:  Cancer Invest        ISSN: 0735-7907            Impact factor:   2.176


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  61 in total

1.  Tyrosyl-DNA phosphodiesterase 1 (TDP1) repairs DNA damage induced by topoisomerases I and II and base alkylation in vertebrate cells.

Authors:  Junko Murai; Shar-yin N Huang; Benu Brata Das; Thomas S Dexheimer; Shunichi Takeda; Yves Pommier
Journal:  J Biol Chem       Date:  2012-02-27       Impact factor: 5.157

2.  Embryotoxicity induced by alkylating agents: 6. DNA adduct formation induced by methylnitrosourea in mouse embryos.

Authors:  G Bochert; T Platzek; U Rahm; D Neubert
Journal:  Arch Toxicol       Date:  1991       Impact factor: 5.153

3.  Dietary cooked navy beans and their fractions attenuate colon carcinogenesis in azoxymethane-induced ob/ob mice.

Authors:  Gerd Bobe; Kathleen G Barrett; Roycelynn A Mentor-Marcel; Umberto Saffiotti; Matthew R Young; Nancy H Colburn; Paul S Albert; Maurice R Bennink; Elaine Lanza
Journal:  Nutr Cancer       Date:  2008       Impact factor: 2.900

4.  A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damage.

Authors:  Michael Chang; Mohammed Bellaoui; Charles Boone; Grant W Brown
Journal:  Proc Natl Acad Sci U S A       Date:  2002-12-13       Impact factor: 11.205

5.  DNA strand breaks and death of thymocytes induced by N-methyl-N-nitrosourea.

Authors:  T Ogiu; H Fukami; M Nishimura
Journal:  J Cancer Res Clin Oncol       Date:  1992       Impact factor: 4.553

6.  Repair of O4-alkylthymine by O6-alkylguanine-DNA alkyltransferases.

Authors:  Qingming Fang; Sreenivas Kanugula; Julie L Tubbs; John A Tainer; Anthony E Pegg
Journal:  J Biol Chem       Date:  2009-12-21       Impact factor: 5.157

7.  Competency in mismatch repair prohibits clonal expansion of cancer cells treated with N-methyl-N'-nitro-N-nitrosoguanidine.

Authors:  J M Carethers; M T Hawn; D P Chauhan; M C Luce; G Marra; M Koi; C R Boland
Journal:  J Clin Invest       Date:  1996-07-01       Impact factor: 14.808

8.  Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice.

Authors:  Jun Zhang; Brigid Stirling; Stephane T Temmerman; Chi A Ma; Ivan J Fuss; Jonathan M J Derry; Ashish Jain
Journal:  J Clin Invest       Date:  2006-10-19       Impact factor: 14.808

9.  Antiproliferative and apoptotic-inducing potential of ellagic acid against 1,2-dimethyl hydrazine-induced colon tumorigenesis in Wistar rats.

Authors:  Syed Umesalma; Ponnuraj Nagendraprabhu; Ganapasam Sudhandiran
Journal:  Mol Cell Biochem       Date:  2013-11-27       Impact factor: 3.396

Review 10.  DNA adducts by N-nitroso compounds.

Authors:  M Wiessler
Journal:  J Cancer Res Clin Oncol       Date:  1986       Impact factor: 4.553

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