Literature DB >> 6732903

Takaokamycin, a new peptide antibiotic produced by Streptomyces sp.

S Omura, H Mamada, N J Wang, N Imamura, R Oiwa, Y Iwai, N Muto.   

Abstract

A new peptide antibiotic named takaokamycin was isolated from a fermentation broth of Streptomyces sp. AC-1978, a soil isolate. It exhibits antibacterial activity against some Gram-positive bacteria. The molecular weight was found to be 1,130 on the basis of elemental analysis, FD-mass spectrum and 1H and 13C NMR. Acid hydrolysate of takaokamycin contains isoleucine, threonine and unidentified amino acids.

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Year:  1984        PMID: 6732903     DOI: 10.7164/antibiotics.37.700

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  2 in total

Review 1.  Structure and noncanonical chemistry of nonribosomal peptide biosynthetic machinery.

Authors:  Heather L Condurso; Steven D Bruner
Journal:  Nat Prod Rep       Date:  2012-06-25       Impact factor: 13.423

Review 2.  Philosophy of new drug discovery.

Authors:  S Omura
Journal:  Microbiol Rev       Date:  1986-09
  2 in total

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