Literature DB >> 6710076

Are all gliadins toxic in coeliac disease? An in vitro study of alpha, beta, gamma, and w gliadins.

P D Howdle, P J Ciclitira, F G Simpson, M S Losowsky.   

Abstract

The toxicity of alpha, beta, gamma, and w gliadins for small-intestinal mucosa has been assessed by means of an organ culture technique. The results suggest that all these gliadin fractions are toxic to coeliac mucosa in vitro.

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Year:  1984        PMID： 6710076

Source DB:  PubMed          Journal:  Scand J Gastroenterol        ISSN： 0036-5521            Impact factor:   2.423


  12 in total

1.  Evidence for the role of a human intestinal adenovirus in the pathogenesis of coeliac disease.

Authors:  M F Kagnoff; Y J Paterson; P J Kumar; D D Kasarda; F R Carbone; D J Unsworth; R K Austin
Journal:  Gut       Date:  1987-08       Impact factor: 23.059

2.  Immunoglobulin production by coeliac biopsies in organ culture.

Authors:  G M Wood; S Shires; P D Howdle; M S Losowsky
Journal:  Gut       Date:  1986-10       Impact factor: 23.059

Review 3.  Investigation of cereal toxicity in coeliac disease.

Authors:  P J Ciclitira; H J Ellis
Journal:  Postgrad Med J       Date:  1987-09       Impact factor: 2.401

Review 4.  Organ culture of gastrointestinal mucosa--a technique for the study of the human gastrointestinal tract.

Authors:  P D Howdle
Journal:  Postgrad Med J       Date:  1984-10       Impact factor: 2.401

Review 5.  Latest in vitro and in vivo models of celiac disease.

Authors:  Samantha Stoven; Joseph A Murray; Eric V Marietta
Journal:  Expert Opin Drug Discov       Date:  2013-01-08       Impact factor: 6.098

6.  Wheat deficient in gliadins: promising tool for treatment of coeliac disease.

Authors:  M Frisoni; G R Corazza; D Lafiandra; E De Ambrogio; C Filipponi; F Bonvicini; E Borasio; E Porceddu; G Gasbarrini
Journal:  Gut       Date:  1995-03       Impact factor: 23.059

7.  Coeliac disease: characterisation of monoclonal antibodies raised against a synthetic peptide corresponding to amino acid residues 206-217 of A-gliadin.

Authors:  H J Ellis; A P Doyle; R P Sturgess; P J Ciclitira
Journal:  Gut       Date:  1992-11       Impact factor: 23.059

8.  Organ culture of fetal rat small intestine for testing gluten toxicity: a reappraisal.

Authors:  G M Wood; P D Howdle; M S Losowsky
Journal:  Br J Exp Pathol       Date:  1987-02

9.  A radioimmunoassay for wheat gliadin to assess the suitability of gluten free foods for patients with coeliac disease.

Authors:  P J Ciclitira; H J Ellis; D J Evans; E S Lennox
Journal:  Clin Exp Immunol       Date:  1985-03       Impact factor: 4.330

10.  A catalogue of Triticum monococcum genes encoding toxic and immunogenic peptides for celiac disease patients.

Authors:  Patrizia Vaccino; Heinz-Albert Becker; Andrea Brandolini; Francesco Salamini; Benjamin Kilian
Journal:  Mol Genet Genomics       Date:  2008-12-23       Impact factor: 3.291
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