Literature DB >> 7698695

Wheat deficient in gliadins: promising tool for treatment of coeliac disease.

M Frisoni1, G R Corazza, D Lafiandra, E De Ambrogio, C Filipponi, F Bonvicini, E Borasio, E Porceddu, G Gasbarrini.   

Abstract

The toxicity of two varieties of bread wheat, one poor in alpha and beta gliadins and the other poor in alpha, beta, gamma, and omega gliadins, has been tested. The peptic-tryptic digest of these wheats was assessed using coeliac mucosa in an in vitro organ culture system. A significantly lower toxicity was found in respect of bread wheat containing all gliadin fractions. These results suggest new opportunities for the treatment of coeliac disease.

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Year:  1995        PMID： 7698695      PMCID： PMC1382448          DOI： 10.1136/gut.36.3.375

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


  21 in total

1.  An in vitro model of gluten-sensitive enteropathy. Effect of gliadin on intestinal epithelial cells of patients with gluten-sensitive enteropathy in organ culture.

Authors:  Z M Falchuk; R L Gebhard; C Sessoms; W Strober
Journal:  J Clin Invest       Date:  1974-02       Impact factor: 14.808

2.  Starch gel electrophoresis of wheat gluten proteins with concentrated urea.

Authors:  J H WOYCHIK; J A BOUNDY; R J DIMLER
Journal:  Arch Biochem Biophys       Date:  1961-09       Impact factor: 4.013

3.  Gluten-induced enteropathy: the effect of partially digested gluten.

Authors:  A C FRAZER; R F FLETCHER; C A ROSS; B SHAW; H G SAMMONS; R SCHNEIDER
Journal:  Lancet       Date:  1959-09-05       Impact factor: 79.321

Review 4.  Celiac sprue.

Authors:  J S Trier
Journal:  N Engl J Med       Date:  1991-12-12       Impact factor: 91.245

5.  Celiac sprue and refractory sprue.

Authors:  J S Trier; Z M Falchuk; M C Carey; D S Schreiber
Journal:  Gastroenterology       Date:  1978-08       Impact factor: 22.682

6.  Malignancy in coeliac disease--effect of a gluten free diet.

Authors:  G K Holmes; P Prior; M R Lane; D Pope; R N Allan
Journal:  Gut       Date:  1989-03       Impact factor: 23.059

7.  Gluten sensitivity of small intestinal mucosa in vitro: quantitative assessment of histologic change.

Authors:  P D Howdle; G R Corazza; A W Bullen; M S Losowsky
Journal:  Gastroenterology       Date:  1981-03       Impact factor: 22.682

8.  Celiac disease: parental knowledge and attitudes of dietary compliance.

Authors:  O Anson; Z Weizman; N Zeevi
Journal:  Pediatrics       Date:  1990-01       Impact factor: 7.124

9.  Follow-up study of coeliac disease.

Authors:  P E Mortimer; J S Stewart; A P Norman; C C Booth
Journal:  Br Med J       Date:  1968-07-06

10.  Clinical testing of bread made from nullisomic 6A wheats in coeliac patients.

Authors:  P J Ciclitira; J O Hunter; E S Lennox
Journal:  Lancet       Date:  1980-08-02       Impact factor: 79.321
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  5 in total

Review 1.  Celiac disease: advances in treatment via gluten modification.

Authors:  Samantha Stoven; Joseph A Murray; Eric Marietta
Journal:  Clin Gastroenterol Hepatol       Date:  2012-06-19       Impact factor: 11.382

Review 2.  Celiac disease: understanding the gluten-free diet.

Authors:  Karla A Bascuñán; María Catalina Vespa; Magdalena Araya
Journal:  Eur J Nutr       Date:  2016-06-22       Impact factor: 5.614

3.  Variable Immunogenic Potential of Wheat: Prospective for Selection of Innocuous Varieties for Celiac Disease Patients via in vitro Approach.

Authors:  Jasmine Grover; Parveen Chhuneja; Vandana Midha; Jean Eric Ghia; Dipak Deka; Chandra Shekhar Mukhopadhyay; Neena Sood; Ramit Mahajan; Arshdeep Singh; Ramneek Verma; Ekta Bansal; Ajit Sood
Journal:  Front Immunol       Date:  2019-02-04       Impact factor: 7.561

4.  Reduced-gliadin wheat bread: an alternative to the gluten-free diet for consumers suffering gluten-related pathologies.

Authors:  Javier Gil-Humanes; Fernando Pistón; Rossana Altamirano-Fortoul; Ana Real; Isabel Comino; Carolina Sousa; Cristina M Rosell; Francisco Barro
Journal:  PLoS One       Date:  2014-03-12       Impact factor: 3.240

5.  Improving wheat to remove coeliac epitopes but retain functionality.

Authors:  Peter R Shewry; Arthur S Tatham
Journal:  J Cereal Sci       Date:  2016-01       Impact factor: 3.616
  5 in total

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