Literature DB >> 669824

Toxicity of emulsified trehalose-6,6'-dimycolate (cord factor) in mice depends on size distribution of mineral oil droplets.

E Yarkoni, H J Rapp.   

Abstract

Toxicity of emulsified trehalose-6,6'-dimycolate administered intravenously into mice depended on the size distribution of the mineral oil droplets. Emulsions containing the greatest number of the largest oil droplets were the most toxic. Emulsions of trehalose-6,6'-dimycolate made with peanut oil or with olive oil were less toxic than those made with mineral oil.

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Year:  1978        PMID： 669824      PMCID： PMC421937          DOI： 10.1128/iai.20.3.856-860.1978

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  7 in total

1.  Granuloma formation in lungs of mice after intravenous administration of emulsified trehalose-6,6'-dimycolate (cord factor): reaction intensity depends on size distribution of the oil droplets.

Authors:  E Yarkoni; H J Rapp
Journal:  Infect Immun       Date:  1977-11       Impact factor: 3.441

2.  Failure of trehalose-6,6'-dimycolate (P3 or cord factor) to enhance endotoxin lethality in mice.

Authors:  E Yarkoni; M S Meltzer; H J Rapp
Journal:  Infect Immun       Date:  1976-12       Impact factor: 3.441

3.  Tumor regression after intralesional injection of emulsified trehalose-6,6'-dimycolate (cord factor): efficacy increases with oil concentration.

Authors:  E Yarkoni; M S Meltzer; H J Rapp
Journal:  Int J Cancer       Date:  1977-06-15       Impact factor: 7.396

4.  Enhancement of nonspecific immunity to bacterial infection by cord factor (6,6'-trehalose dimycolate).

Authors:  M Parant; F Parant; L Chedid; J C Drapier; J F Petit; J Wietzerbin
Journal:  J Infect Dis       Date:  1977-05       Impact factor: 5.226

5.  Acute granulomatous response produced in mice by trehalose-6,6-dimycolate.

Authors:  A Bekierkunst
Journal:  J Bacteriol       Date:  1968-10       Impact factor: 3.490

6.  Synergistic action of cord factor and mycobacterial sulfatides on mitochondria.

Authors:  M Kato; M B Goren
Journal:  Infect Immun       Date:  1974-10       Impact factor: 3.441

7.  Studies on the virulence of tubercle bacilli; variations in virulence effected by tween 80 and thiosemicarbazone.

Authors:  H BLOCH; H NOLL
Journal:  J Exp Med       Date:  1953-01       Impact factor: 14.307
  7 in total
  6 in total

1.  Influence of oil and Tween concentrations on enhanced endotoxin lethality in mice pretreated with emulsified trehalose-6,6'-dimycolate (cord factor).

Authors:  E Yarkoni; H J Rapp
Journal:  Infect Immun       Date:  1979-05       Impact factor: 3.441

2.  Effect of sulfolipid I on trehalose-6,6'-dimycolate (cord factor) toxicity and antitumor activity.

Authors:  E Yarkoni; M B Goren; H J Rapp
Journal:  Infect Immun       Date:  1979-05       Impact factor: 3.441

3.  Regression of a murine fibrosarcoma after intralesional injection of a synthetic C39 glycolipid related to cord factor.

Authors:  E Yarkoni; H J Rapp; J Polonsky; J Varenne; E Lederer
Journal:  Infect Immun       Date:  1979-11       Impact factor: 3.441

4.  In vitro cytokine stimulation assay for glycolipid biosurfactant from Rhodococcus ruber: role of monocyte adhesion.

Authors:  Sergey V Gein; Maria S Kuyukina; Irena B Ivshina; Tatiana A Baeva; Valery A Chereshnev
Journal:  Cytotechnology       Date:  2011-08-20       Impact factor: 2.058

5.  Regression of a transplanted guinea pig hepatoma after intralesional injection of an emulsified mixture of endotoxin and mycobacterial sulfolipid.

Authors:  E Yarkoni; M B Goren; H J Rapp
Journal:  Infect Immun       Date:  1979-05       Impact factor: 3.441

Review 6.  Macrophage-Bacteria Interactions-A Lipid-Centric Relationship.

Authors:  Ooiean Teng; Candice Ke En Ang; Xue Li Guan
Journal:  Front Immunol       Date:  2017-12-20       Impact factor: 7.561
  6 in total

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