Literature DB >> 6689503

Structural and evolutionary analysis of the two chimpanzee alpha-globin mRNAs.

S A Liebhaber, K A Begley.   

Abstract

Two distinct alpha-globin mRNAs were detected in chimpanzee reticulocyte mRNA using a primer extension assay. DNA copies of these two mRNAs were cloned in the bacterial plasmid pBR322, and their sequence was determined. The two alpha-globin mRNAs have obvious structural homology to the two human alpha-globin mRNAs, alpha 1 and alpha 2. Comparison of the two chimpanzee alpha-globin mRNAs to each other and to their corresponding human counterparts revealed evidence of a recent gene conversion in the human alpha-globin complex and a marked heterogeneity in the rate of structural divergence within the alpha-globin gene.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6689503      PMCID： PMC326634          DOI： 10.1093/nar/11.24.8915

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  31 in total

1.  Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.

Authors:  M Grunstein; D S Hogness
Journal:  Proc Natl Acad Sci U S A       Date:  1975-10       Impact factor: 11.205

2.  Rapid evolution of animal mitochondrial DNA.

Authors:  W M Brown; M George; A C Wilson
Journal:  Proc Natl Acad Sci U S A       Date:  1979-04       Impact factor: 11.205

3.  Deletion of alpha-globin genes in haemoglobin-H disease demonstrates multiple alpha-globin structural loci.

Authors:  Y W Kan; A M Dozy; H E Varmus; J M Taylor; J P Holland; L E Lie-Injo; J Ganesan; D Todd
Journal:  Nature       Date:  1975-05-15       Impact factor: 49.962

4.  A new method for sequencing DNA.

Authors:  A M Maxam; W Gilbert
Journal:  Proc Natl Acad Sci U S A       Date:  1977-02       Impact factor: 11.205

5.  Prolonged incubation in calcium chloride improves the competence of Escherichia coli cells.

Authors:  M Dagert; S D Ehrlich
Journal:  Gene       Date:  1979-05       Impact factor: 3.688

6.  Organization of the alpha-globin genes in the Chinese alpha-thalassemia syndromes.

Authors:  S H Embury; R V Lebo; A M Dozy; Y W Kan
Journal:  J Clin Invest       Date:  1979-06       Impact factor: 14.808

7.  A complementation analysis of the restriction and modification of DNA in Escherichia coli.

Authors:  H W Boyer; D Roulland-Dussoix
Journal:  J Mol Biol       Date:  1969-05-14       Impact factor: 5.469

8.  The duplicated human alpha globin genes lie close together in cellular DNA.

Authors:  S H Orkin
Journal:  Proc Natl Acad Sci U S A       Date:  1978-12       Impact factor: 11.205

Review 9.  Biochemical evolution.

Authors:  A C Wilson; S S Carlson; T J White
Journal:  Annu Rev Biochem       Date:  1977       Impact factor: 23.643

10.  Authentic beta-globin mRNA sequences in homozygous betaO-thalassemia.

Authors:  G F Temple; J C Chang; Y W Kan
Journal:  Proc Natl Acad Sci U S A       Date:  1977-07       Impact factor: 11.205
View more
  16 in total

1.  DNA hybridization as a guide to phylogeny: chemical and physical limits.

Authors:  C W Schmid; J Marks
Journal:  J Mol Evol       Date:  1990-03       Impact factor: 2.395

2.  Anomalous and selective DNA mutations of the Old World monkey alpha-globin genes.

Authors:  J P Shaw; J Marks; C C Shen; C K Shen
Journal:  Proc Natl Acad Sci U S A       Date:  1989-02       Impact factor: 11.205

3.  Two nuclear location signals in the influenza virus NS1 nonstructural protein.

Authors:  D Greenspan; P Palese; M Krystal
Journal:  J Virol       Date:  1988-08       Impact factor: 5.103

4.  The orangutan adult alpha-globin gene locus: duplicated functional genes and a newly detected member of the primate alpha-globin gene family.

Authors:  J Marks; J P Shaw; C K Shen
Journal:  Proc Natl Acad Sci U S A       Date:  1986-03       Impact factor: 11.205

5.  Variation among human 28S ribosomal RNA genes.

Authors:  I L Gonzalez; J L Gorski; T J Campen; D J Dorney; J M Erickson; J E Sylvester; R D Schmickel
Journal:  Proc Natl Acad Sci U S A       Date:  1985-11       Impact factor: 11.205

6.  Independent recombination events between the duplicated human alpha globin genes; implications for their concerted evolution.

Authors:  D R Higgs; A V Hill; D K Bowden; D J Weatherall; J B Clegg
Journal:  Nucleic Acids Res       Date:  1984-09-25       Impact factor: 16.971

7.  Comparative sequence analysis as a tool for studying the secondary structure of mRNAs.

Authors:  M F Browner; C B Lawrence
Journal:  Nucleic Acids Res       Date:  1985-12-09       Impact factor: 16.971

8.  Translational profiles of alpha 1-, alpha 2-, and beta-globin messenger ribonucleic acids in human reticulocytes.

Authors:  S H Shakin; S A Liebhaber
Journal:  J Clin Invest       Date:  1986-10       Impact factor: 14.808

9.  Compensatory increase in alpha 1-globin gene expression in individuals heterozygous for the alpha-thalassemia-2 deletion.

Authors:  S A Liebhaber; F E Cash; D M Main
Journal:  J Clin Invest       Date:  1985-09       Impact factor: 14.808

10.  Molecular basis for nondeletion alpha-thalassemia in American blacks. Alpha 2(116GAG----UAG).

Authors:  S A Liebhaber; M B Coleman; J G Adams; F E Cash; M H Steinberg
Journal:  J Clin Invest       Date:  1987-07       Impact factor: 14.808
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.