Literature DB >> 6689324

Novel antitumor agents CI-920, PD 113,270 and PD 113,271. II. Isolation and characterization.

S S Stampwala, R H Bunge, T R Hurley, N E Willmer, A J Brankiewicz, C E Steinman, T A Smitka, J C French.   

Abstract

A complex of structurally related compounds that exhibit in vivo antileukemic activity was isolated from fermentation broths of a new streptomycete. The components of this complex are water soluble phosphate esters containing a conjugated triene system. The isolation and characterization of three of these components are described.

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Year:  1983        PMID： 6689324     DOI： 10.7164/antibiotics.36.1601

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  16 in total

1.  Dopamine-dependent tuning of striatal inhibitory synaptogenesis.

Authors:  Darren Goffin; Afia B Ali; Nazir Rampersaud; Alexander Harkavyi; Celine Fuchs; Peter S Whitton; Angus C Nairn; Jasmina N Jovanovic
Journal:  J Neurosci       Date:  2010-02-24       Impact factor: 6.167

Review 2.  Synthetic Strategies Employed for the Construction of Fostriecin and Related Natural Products.

Authors:  Barry M Trost; Joshua D Knopf; Cheyenne S Brindle
Journal:  Chem Rev       Date:  2016-12-08       Impact factor: 60.622

3.  Coibacins A and B: total synthesis and stereochemical revision.

Authors:  Vânia M T Carneiro; Carolina M Avila; Marcy J Balunas; William H Gerwick; Ronaldo A Pilli
Journal:  J Org Chem       Date:  2014-01-09       Impact factor: 4.354

4.  In vivo and in vitro anticancer activity of the structurally novel and highly potent antibiotic CI-940 and its hydroxy analog (PD 114,721).

Authors:  B J Roberts; K L Hamelehle; J S Sebolt; W R Leopold
Journal:  Cancer Chemother Pharmacol       Date:  1986       Impact factor: 3.333

5.  Total synthesis of fostriecin: via a regio- and stereoselective polyene hydration, oxidation, and hydroboration sequence.

Authors:  Dong Gao; George A O'Doherty
Journal:  Org Lett       Date:  2010-09-03       Impact factor: 6.005

6.  Studies on the biochemical mechanism of the novel antitumor agent, CI-920.

Authors:  D W Fry; T J Boritzki; R C Jackson
Journal:  Cancer Chemother Pharmacol       Date:  1984       Impact factor: 3.333

7.  Total and Formal Syntheses of Fostriecin.

Authors:  Gao Dong; Bohui Li; George O'Doherty
Journal:  Org Chem Front       Date:  2020-10-12       Impact factor: 5.281

8.  Structural and stereochemical analysis of a modular polyketide synthase ketoreductase domain required for the generation of a cis-alkene.

Authors:  Shilah A Bonnett; Jonathan R Whicher; Kancharla Papireddy; Galina Florova; Janet L Smith; Kevin A Reynolds
Journal:  Chem Biol       Date:  2013-06-20

9.  Enantioselective synthesis of 2-methyl-1,2-syn- and 2-methyl-1,2-anti-3-butenediols via allene hydroboration-aldehyde allylboration reaction sequences.

Authors:  Ming Chen; Masaki Handa; William R Roush
Journal:  J Am Chem Soc       Date:  2009-10-21       Impact factor: 15.419

10.  Crystal structures of protein phosphatase-1 bound to nodularin-R and tautomycin: a novel scaffold for structure-based drug design of serine/threonine phosphatase inhibitors.

Authors:  Matthew S Kelker; Rebecca Page; Wolfgang Peti
Journal:  J Mol Biol       Date:  2008-11-01       Impact factor: 5.469
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