Literature DB >> 28027648

Synthetic Strategies Employed for the Construction of Fostriecin and Related Natural Products.

Barry M Trost1, Joshua D Knopf2, Cheyenne S Brindle2.   

Abstract

Fostriecin and related natural products present a significant challenge for synthetic chemists due to their structural complexity and chemical sensitivity. This review will chronicle the successful efforts of synthetic chemists in the construction of these biologically active molecules. Key carbon-carbon bond forming reactions will be highlighted, as well as the methods used to install the numerous stereocenters present in this class of compounds.

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Year:  2016        PMID： 28027648      PMCID： PMC5720176          DOI： 10.1021/acs.chemrev.6b00488

Source DB:  PubMed          Journal:  Chem Rev        ISSN： 0009-2665            Impact factor:   60.622


  127 in total

1.  Direct catalytic asymmetric aldol additions of methyl ynones. Spontaneous reversal in the sense of enantioinduction.

Authors:  Barry M Trost; Alec Fettes; Brock T Shireman
Journal:  J Am Chem Soc       Date:  2004-03-10       Impact factor: 15.419

Review 2.  Catalytic function of DNA topoisomerase II.

Authors:  N Osheroff; E L Zechiedrich; K C Gale
Journal:  Bioessays       Date:  1991-06       Impact factor: 4.345

3.  Screening for apoptosis inducers in microbial products and induction of apoptosis by cytostatin.

Authors:  K Yamazaki; M Amemiya; M Ishizuka; T Takeuchi
Journal:  J Antibiot (Tokyo)       Date:  1995-10       Impact factor: 2.649

4.  Phoslactomycin targets cysteine-269 of the protein phosphatase 2A catalytic subunit in cells.

Authors:  Takayuki Teruya; Siro Simizu; Naoki Kanoh; Hiroyuki Osada
Journal:  FEBS Lett       Date:  2005-04-25       Impact factor: 4.124

5.  Total Synthesis of Myxalamide A.

Authors:  Anna K. Mapp; Clayton H. Heathcock
Journal:  J Org Chem       Date:  1999-01-08       Impact factor: 4.354

6.  Formal synthesis of leustroducsin B via Reformatsky/Claisen condensation of silyl glyoxylates.

Authors:  Stephen N Greszler; Justin T Malinowski; Jeffrey S Johnson
Journal:  Org Lett       Date:  2011-05-17       Impact factor: 6.005

7.  Studies on new phosphate ester antifungal antibiotics phoslactomycins. II. Structure elucidation of phoslactomycins A to F.

Authors:  S Fushimi; K Furihata; H Seto
Journal:  J Antibiot (Tokyo)       Date:  1989-07       Impact factor: 2.649

8.  Asymmetric total synthesis of (+)-phoslactomycin B.

Authors:  Setsuya Shibahara; Masataka Fujino; Yasumasa Tashiro; Keisuke Takahashi; Jun Ishihara; Susumi Hatakeyama
Journal:  Org Lett       Date:  2008-05-08       Impact factor: 6.005

9.  A Highly Convergent Total Synthesis of Leustroducsin B.

Authors:  Barry M Trost; Berenger Biannic; Cheyenne S Brindle; B Michael O'Keefe; Thomas J Hunter; Ming-Yu Ngai
Journal:  J Am Chem Soc       Date:  2015-09-01       Impact factor: 15.419

10.  Differential induction of apoptosis in B16 melanoma and EL-4 lymphoma cells by cytostatin and bactobolin.

Authors:  M Kawada; M Amemiya; M Ishizuka; T Takeuchi
Journal:  Jpn J Cancer Res       Date:  1999-02
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  5 in total

1.  Total and Formal Syntheses of Fostriecin.

Authors:  Gao Dong; Bohui Li; George O'Doherty
Journal:  Org Chem Front       Date:  2020-10-12       Impact factor: 5.281

2.  Total Synthesis and Structural Validation of Phosdiecin A via Asymmetric Alcohol-Mediated Carbonyl Reductive Coupling.

Authors:  Franco Della-Felice; Ariel M Sarotti; Michael J Krische; Ronaldo A Pilli
Journal:  J Am Chem Soc       Date:  2019-08-21       Impact factor: 15.419

3.  Protein Phosphatase 2A Improves Cardiac Functional Response to Ischemia and Sepsis.

Authors:  Ulrich Gergs; Tina Jahn; Nico Schulz; Claudia Großmann; Uwe Rueckschloss; Uta Demus; Igor B Buchwalow; Joachim Neumann
Journal:  Int J Mol Sci       Date:  2022-04-23       Impact factor: 6.208

4.  The Difference a Single Atom Can Make: Synthesis and Design at the Chemistry-Biology Interface.

Authors:  Dale L Boger
Journal:  J Org Chem       Date:  2017-10-13       Impact factor: 4.354

5.  Lactomycins A-C, Dephosphorylated Phoslactomycin Derivatives that Inhibit Cathepsin B, from the Marine-derived Streptomyces sp. ACT232.

Authors:  Yi Sun; Rogie Royce Carandang; Yuta Harada; Shigeru Okada; Kazutoshi Yoshitake; Shuichi Asakawa; Yuichi Nogi; Shigeki Matsunaga; Kentaro Takada
Journal:  Mar Drugs       Date:  2018-02-21       Impact factor: 5.118
  5 in total

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