Literature DB >> 6688579

Peptide histidine isoleucine (PHI). A secretagogue in porcine intestine.

A A Anagnostides, K Manolas, N D Christofides, Y Yiangou, R B Welbourn, S R Bloom, V S Chadwick.   

Abstract

PHI (peptide histidine isoleucine) is a recently identified porcine peptide, present in large quantities in the intestine, which has sequence homologies with VIP, an established intestinal secretagogue, and with secretin, glucagon, and GIP. The effects of PHI on jejunal, ileal, and colonic fluid and electrolyte transport were studied in the pig. PHI appears to be an intestinal secretagogue inducing a reversible net secretion of fluid and electrolytes in jejunum and ileum and less marked effects in the colon.

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Year:  1983        PMID： 6688579     DOI： 10.1007/bf01317039

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN： 0163-2116            Impact factor:   3.199


  10 in total

1.  Are peptide histidine isoleucine and vasoactive intestinal peptide co-synthesised in the same pro-hormone?

Authors:  N D Christofides; Y Yiangou; M A Blank; K Tatemoto; J M Polak; S R Bloom
Journal:  Lancet       Date:  1982-12-18       Impact factor: 79.321

2.  Actions of a newly isolated intestinal peptide PHI on pancreatic acini.

Authors:  R T Jensen; K Tatemoto; V Mutt; G F Lemp; J D Gardner
Journal:  Am J Physiol       Date:  1981-12

3.  Vascular effects of the peptides PYY and PHI: comparison with APP and VIP.

Authors:  J M Lundberg; K Tatemoto
Journal:  Eur J Pharmacol       Date:  1982-09-10       Impact factor: 4.432

4.  Actions of a new peptide from porcine intestine (PHI) on pancreatic secretion in the rat and turkey.

Authors:  R Dimaline; G J Dockray
Journal:  Life Sci       Date:  1980-11-24       Impact factor: 5.037

5.  Radioimmunoassay and intramural distribution of PHI-IR in human intestine.

Authors:  N D Christofides; Y Yiangou; E Aarons; G L Ferri; K Tatemoto; J M Polak; S R Bloom
Journal:  Dig Dis Sci       Date:  1983-06       Impact factor: 3.199

6.  Porcine peptide having N-terminal histidine and C-terminal isoleucine amide (PHI): vasoactive intestinal peptide (VIP) and secretin-like effects in different tissues from the rat.

Authors:  D Bataille; C Gespach; M Laburthe; B Amiranoff; K Tatemoto; N Vauclin; V Mutt; G Rosselin
Journal:  FEBS Lett       Date:  1980-06-02       Impact factor: 4.124

7.  Effect of VIP infusion in water and ion transport in the human jejunum.

Authors:  G J Krejs; J S Fordtran; J Fahrenkrug; O B Schaffalitzky de Muckadell; J E Fischer; C S Humphrey; T M O'Dorisio; S I Said; J H Walsh; A A Shulkes
Journal:  Gastroenterology       Date:  1980-04       Impact factor: 22.682

8.  Experimental evidence for vasoactive intestinal peptide as the cause of the watery diarrhea syndrome.

Authors:  I M Modlin; S R Bloom; S J Mitchell
Journal:  Gastroenterology       Date:  1978-12       Impact factor: 22.682

9.  Isolation and characterization of the intestinal peptide porcine PHI (PHI-27), a new member of the glucagon--secretin family.

Authors:  K Tatemoto; V Mutt
Journal:  Proc Natl Acad Sci U S A       Date:  1981-11       Impact factor: 11.205

10.  Isolation of two novel candidate hormones using a chemical method for finding naturally occurring polypeptides.

Authors:  K Tatemoto; V Mutt
Journal:  Nature       Date:  1980-06-05       Impact factor: 49.962
  10 in total
  3 in total

1.  Excitatory actions of peptide histidine isoleucine on thalamic relay neurons.

Authors:  Sang-Hun Lee; Charles L Cox
Journal:  Neuropharmacology       Date:  2008-08-30       Impact factor: 5.250

2.  Immunocytochemical evidence for the presence of "mammalian" neurohormonal peptides in neurones of the tapeworm Diphyllobothrium dendriticum.

Authors:  M K Gustafsson; M A Lehtonen; F Sundler
Journal:  Cell Tissue Res       Date:  1986       Impact factor: 5.249

3.  Peptide histidine isoleucine-like immunoreactivity release from the rat gastric fundus.

Authors:  D Currò; P Preziosi; E Ragazzoni; G Ciabattoni
Journal:  Br J Pharmacol       Date:  1994-10       Impact factor: 8.739
  3 in total

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