Literature DB >> 6686430

Toxicity of the Alternaria metabolites alternariol, alternariol methyl ether, altenuene, and tenuazonic acid in the chicken embryo assay.

G F Griffin, F S Chu.   

Abstract

The effects in the chicken embryo assay of four Alternaria metabolites (alternariol [AOH], alternariol methyl ether [AME], altenuene [ALT], and tenuazonic acid [TA]) were investigated. Administered to 7-day-old chicken embryos by yolk sac injection, AOH, AME, and ALT caused no mortality or teratogenic effect at doses up to 1,000, 500, and 1,000 micrograms per egg, respectively. TA exhibited a calculated 50% lethal dose of 548 micrograms per egg, with no teratogenic effect observed at either lethal or sublethal doses.

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Year:  1983        PMID： 6686430      PMCID： PMC239585          DOI： 10.1128/aem.46.6.1420-1422.1983

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  13 in total

1.  Collaborative study of the chicken embryo bioassay for aflatoxin B1.

Authors:  M J Verrett; J Winbush; E F Reynaldo; W F Scott
Journal:  J Assoc Off Anal Chem       Date:  1973-07

2.  Mycotoxicosis: toxicity to chicks of Alternaria longipes isolated from tobacco.

Authors:  B Doupnik; E K Sobers
Journal:  Appl Microbiol       Date:  1968-10

3.  Toxicity of Alternaria metabolites found in weathered sorghum grain at harvest.

Authors:  D B Sauer; L M Seitz; R Burroughs; H E Mohr; J L West; R J Milleret; H D Anthony
Journal:  J Agric Food Chem       Date:  1978 Nov-Dec       Impact factor: 5.279

4.  Mycotoxin production by Alternaria species grown on apples, tomatoes, and blueberries.

Authors:  E E Stinson; D D Bills; S F Osman; J Siciliano; M J Ceponis; E G Heisler
Journal:  J Agric Food Chem       Date:  1980 Sep-Oct       Impact factor: 5.279

5.  Effect of tenuazonic acid on young chickens.

Authors:  J J Giambrone; N D Davis; U L Diener
Journal:  Poult Sci       Date:  1978-11       Impact factor: 3.352

6.  Mycotoxin production in whole tomatoes, apples, oranges, and lemons.

Authors:  E E Stinson; S F Osman; E G Heisler; J Siciliano; D D Bills
Journal:  J Agric Food Chem       Date:  1981 Jul-Aug       Impact factor: 5.279

7.  Toxigenicity of fungi from grain sorghum.

Authors:  U L Diener; G Morgan-Jones; R E Wagener; N D Davis
Journal:  Mycopathologia       Date:  1981-07-10       Impact factor: 2.574

8.  Toxins of molds from decaying tomato fruit.

Authors:  J Harwig; P M Scott; D R Stoltz; B J Blanchfield
Journal:  Appl Environ Microbiol       Date:  1979-08       Impact factor: 4.792

9.  Tenuazonic acid production by Alternaria alternata and Alternaria tenuissima isolated from cotton.

Authors:  N D Davis; U L Diener; G Morgan-Jones
Journal:  Appl Environ Microbiol       Date:  1977-08       Impact factor: 4.792

10.  Toxicity of metabolites produced by the "Alternaria".

Authors:  R W Pero; H Posner; M Blois; D Harvan; J W Spalding
Journal:  Environ Health Perspect       Date:  1973-06       Impact factor: 9.031
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  12 in total

1.  Alternaria toxin-induced resistance in rose plants against rose aphid (Macrosiphum rosivorum): effect of tenuazonic acid.

Authors:  Fa-zhong Yang; Bin Yang; Bei-bei Li; Chun Xiao
Journal:  J Zhejiang Univ Sci B       Date:  2015-04       Impact factor: 3.066

2.  Effects of dry olive residue transformed by Coriolopsis floccosa (Polyporaceae) on the distribution and dynamic of a culturable fungal soil community.

Authors:  José A Siles; Victor González-Menéndez; Gonzalo Platas; Inmaculada Sampedro; Inmaculada García-Romera; Gerald F Bills
Journal:  Microb Ecol       Date:  2014-01-14       Impact factor: 4.552

3.  Alternariol disturbs oocyte maturation and preimplantation development.

Authors:  Eric J Schoevers; Regiane R Santos; Bernard A J Roelen
Journal:  Mycotoxin Res       Date:  2019-08-31       Impact factor: 3.833

4.  SnPKS19 Encodes the Polyketide Synthase for Alternariol Mycotoxin Biosynthesis in the Wheat Pathogen Parastagonospora nodorum.

Authors:  Yit-Heng Chooi; Mariano Jordi Muria-Gonzalez; Oliver L Mead; Peter S Solomon
Journal:  Appl Environ Microbiol       Date:  2015-05-29       Impact factor: 4.792

5.  Sambutoxin, a new mycotoxin produced by toxic Fusarium isolates obtained from rotted potato tubers.

Authors:  J C Kim; Y W Lee
Journal:  Appl Environ Microbiol       Date:  1994-12       Impact factor: 4.792

6.  TDP-1, a toxic component causing tibial dyschondroplasia in broiler chickens, and trichothecenes from Fusarium roseum 'Graminearum'.

Authors:  Y W Lee; C J Mirocha; D J Shroeder; M M Walser
Journal:  Appl Environ Microbiol       Date:  1985-07       Impact factor: 4.792

Review 7.  Emerging Fusarium and Alternaria Mycotoxins: Occurrence, Toxicity and Toxicokinetics.

Authors:  Sophie Fraeyman; Siska Croubels; Mathias Devreese; Gunther Antonissen
Journal:  Toxins (Basel)       Date:  2017-07-18       Impact factor: 4.546

8.  Multi-mycotoxin screening reveals the occurrence of 139 different secondary metabolites in feed and feed ingredients.

Authors:  Elisabeth Streit; Christina Schwab; Michael Sulyok; Karin Naehrer; Rudolf Krska; Gerd Schatzmayr
Journal:  Toxins (Basel)       Date:  2013-03-08       Impact factor: 4.546

Review 9.  Biosynthesis of α-pyrones.

Authors:  Till F Schäberle
Journal:  Beilstein J Org Chem       Date:  2016-03-24       Impact factor: 2.883

Review 10.  Metabolites from Alternaria fungi and their bioactivities.

Authors:  Jingfeng Lou; Linyun Fu; Youliang Peng; Ligang Zhou
Journal:  Molecules       Date:  2013-05-21       Impact factor: 4.411
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