Literature DB >> 6686209

A genetic component of the variance of N-acetoxy-2-acetylaminofluorene-induced DNA damage in mononuclear leukocytes determined by a twin study.

R W Pero, C Bryngelsson, T Bryngelsson, A Nordén.   

Abstract

The level of N-acetoxy-2-acetylaminofluorene (NA-AAF)-induced unscheduled DNA synthesis and the level of covalent binding of NA-AAF to DNA were determined in the mononuclear leukocytes of monozygotic and diazygotic twin pairs (n = 16 for each type). A statistically significant high degree of heritability was calculated for both parameters which, in turn, indicate genetic control of individual levels of induced DNA damage by NA-AAF.

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Year:  1983        PMID： 6686209     DOI： 10.1007/bf00286659

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  28 in total

1.  Heredity in hypertension.

Authors:  R PLATT
Journal:  Lancet       Date:  1963-04-27       Impact factor: 79.321

2.  Aryl-hydrocarbon hydroxylase activity in lymphocytes from lung cancer patients and normal controls.

Authors:  H A Guirgis; H T Lynch; T Mate; R E Harris; I Wells; L Caha; J Anderson; K Maloney; L Rankin
Journal:  Oncology       Date:  1976       Impact factor: 2.935

3.  Diagnosis of twin zygosity by mailed questionnaire.

Authors:  S Sarna; J Kaprio; P Sistonen; M Koskenvuo
Journal:  Hum Hered       Date:  1978       Impact factor: 0.444

4.  The hepatic toxicity of isoniazid among rapid and slow acetylators of the drug.

Authors:  G A Ellard; D A Mitchison; D J Girling; A J Nunn; W Fox
Journal:  Am Rev Respir Dis       Date:  1978-09

5.  A new Swedish twin registry containing environmental and medical base line data from about 14,000 same-sexed pairs born 1926-58.

Authors:  P Medlund; R Cederlöf; B Flodérus-Myrhed; L Friberg; S Sörensen
Journal:  Acta Med Scand Suppl       Date:  1976

6.  Reduced capacity for DNA repair synthesis in patients with or genetically predisposed to colorectal cancer.

Authors:  R W Pero; D G Miller; M Lipkin; M Markowitz; S Gupta; S J Winawer; W Enker; R Good
Journal:  J Natl Cancer Inst       Date:  1983-05       Impact factor: 13.506

7.  High blood pressure related to carcinogen-induced unscheduled DNA synthesis, DNA carcinogen binding, and chromosomal aberrations in human lymphocytes.

Authors:  R W Pero; C Bryngelsson; F Mitelman; T Thulin; A Nordén
Journal:  Proc Natl Acad Sci U S A       Date:  1976-07       Impact factor: 11.205

8.  Positive correlation between high aryl hydrocarbon hydroxylase activity and primary lung cancer as analyzed in cryopreserved lymphocytes.

Authors:  R E Kouri; C E McKinney; D J Slomiany; D R Snodgrass; N P Wray; T L McLemore
Journal:  Cancer Res       Date:  1982-12       Impact factor: 12.701

9.  Metabolic studies in vivo with arylamines.

Authors:  E K Weisburger
Journal:  Natl Cancer Inst Monogr       Date:  1981-12

10.  Genetic control of interindividual variations in the inducibility of aryl hydrocarbon hydroxylase in cultured human lymphocytes.

Authors:  S A Atlas; E S Vesell; D W Nebert
Journal:  Cancer Res       Date:  1976-12       Impact factor: 12.701
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  3 in total

1.  Variable continental distribution of polymorphisms in the coding regions of DNA-repair genes.

Authors:  Géraldine Mathonnet; Damian Labuda; Caroline Meloche; Tina Wambach; Maja Krajinovic; Daniel Sinnett
Journal:  J Hum Genet       Date:  2003-11-19       Impact factor: 3.172

Review 2.  Use of cultured human tissues and cells in carcinogenesis research.

Authors:  E W Gabrielson; C C Harris
Journal:  J Cancer Res Clin Oncol       Date:  1985       Impact factor: 4.553

3.  Unscheduled DNA synthesis correlated to alkylation of hemoglobin in individuals occupationally exposed to propylene oxide.

Authors:  R W Pero; S Osterman-Golkar; B Högstedt
Journal:  Cell Biol Toxicol       Date:  1985-10       Impact factor: 6.691
  3 in total

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