Literature DB >> 1012643

Aryl-hydrocarbon hydroxylase activity in lymphocytes from lung cancer patients and normal controls.

H A Guirgis, H T Lynch, T Mate, R E Harris, I Wells, L Caha, J Anderson, K Maloney, L Rankin.   

Abstract

A radiometric assay for the determination of AHH activity in lymphocytes is described. Subjects included eleven male patients with histologically verified lung cancer (nine squamous cell carcinoma and two adenocarcinoma) and eleven age- and sex-matched controls. Lung cancer patients exhibited considerably greater variation and elevated levels of both AHH activity per se and AHH activity adjusted for total cellular DNA than control individuals. Methodology for AHH determinations and implications for lung cancer epidemiology and control are discussed.

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Year:  1976        PMID： 1012643     DOI： 10.1159/000225116

Source DB:  PubMed          Journal:  Oncology        ISSN： 0030-2414            Impact factor:   2.935


  10 in total

1.  Leucoplakia of the oral cavity, smoking and arylhydrocarbon-hydroxylase inducibility.

Authors:  L Andréasson; G Björlin; R Korsgaard; I Mattiasson; E Trell; L Trell
Journal:  Postgrad Med J       Date:  1982-03       Impact factor: 2.401

Review 2.  Genetic predisposition to lung cancer.

Authors:  M R Law
Journal:  Br J Cancer       Date:  1990-02       Impact factor: 7.640

3.  Inducibility of aryl hydrocarbon hydroxylase in cultured human lymphocytes: a study of repeatability.

Authors:  K A Fletcher; D A Evans; M V Canning
Journal:  J Med Genet       Date:  1978-06       Impact factor: 6.318

4.  Aryl hydrocarbon hydroxylase activity in pulmonary alveolar macrophages and lymphocytes from lung cancer and noncancer patients: a correlation with family histories of cancer.

Authors:  T L McLemore; R R Martin; R R Springer; N Wray; E T Cantrell; D L Busbee
Journal:  Biochem Genet       Date:  1979-10       Impact factor: 1.890

5.  A genetic component of the variance of N-acetoxy-2-acetylaminofluorene-induced DNA damage in mononuclear leukocytes determined by a twin study.

Authors:  R W Pero; C Bryngelsson; T Bryngelsson; A Nordén
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132

6.  Enhanced benzo(a)pyrene metabolism and formation of DNA adducts in monocytes of patients with lung cancer.

Authors:  H W Rüdiger; V Heisig; E Hain
Journal:  J Cancer Res Clin Oncol       Date:  1980       Impact factor: 4.553

7.  Human hair follicles and cultured hair follicle keratinocytes as indicators for individual differences in carcinogen metabolism.

Authors:  M W Hukkelhoven; A C Dijkstra; A J Vermorken
Journal:  Arch Toxicol       Date:  1983-08       Impact factor: 5.153

8.  Aryl hydrocarbon hydroxylase induction levels in patients with malignant tumors associated with smoking.

Authors:  R Korsgaard; E Trell; B G Simonsson; G Stiksa; L Janzon; B Hood; J Oldbring
Journal:  J Cancer Res Clin Oncol       Date:  1984       Impact factor: 4.553

Review 9.  Genetic differences in susceptibility to chemically induced myelotoxicity and leukemia.

Authors:  D W Nebert
Journal:  Environ Health Perspect       Date:  1981-06       Impact factor: 9.031

10.  The relationship between aryl hydrocarbon hydroxylase and polymorphisms of the CYP1A1 gene.

Authors:  C Kiyohara; T Hirohata; S Inutsuka
Journal:  Jpn J Cancer Res       Date:  1996-01
  10 in total

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