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Literature DB >> 6615712

The regeneration of rectal epithelium in the rat following wounding with suppositories of polyoxyethylene (23) lauryl ether.

Abstract

The regeneration of the epithelial compartments of the rectal mucosa in rats has been quantified at time intervals up to one week following wounding with suppositories of the surfactant polyoxyethylene-(23)-lauryl ether. Regeneration of glandular tissue was complete within one week of the wounding, with new glands arising from residual gland bases and from surface invagination of empty crypt skeletons and underlying granulation tissue. This method of wounding appears to be particularly useful for the study of epithelial regeneration since there was a minimal connective tissue response to the insult.

Entities: Chemical Species

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Year: 1983 PMID： 6615712 PMCID： PMC2040807

Source DB: PubMed Journal: Br J Exp Pathol ISSN： 0007-1021

11 in total

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Authors: W A FOLEY; L W WATTENBERG
Journal: Arch Pathol Date: 1960-12

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Authors: G LUMB
Journal: Am J Dig Dis Date: 1960-10

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Authors: F HIGHTOWER
Journal: Ann Surg Date: 1958-06 Impact factor: 12.969

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Authors: R J O'CONNOR
Journal: Br J Surg Date: 1956-07 Impact factor: 6.939

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Authors: D R Reeve
Journal: J Anat Date: 1974-11 Impact factor: 2.610

6. Regeneration of the human colon mucosa. Morphological and histochemical study.

Authors: C S Melnyk; R E Braucher; J B Kirsner
Journal: Gastroenterology Date: 1967-06 Impact factor: 22.682

7. Wounds and wound healing.

Authors: T Schrock; F Cerra; P R Hawley; T K Hunt; R L Nichols; R B Samson
Journal: Dis Colon Rectum Date: 1982 Jan-Feb Impact factor: 4.585

8. Relative effects of different surfactants on intestinal absorption and the release of proteins and phospholipids from the tissue.

Authors: D A Whitmore; L G Brookes; K P Wheeler
Journal: J Pharm Pharmacol Date: 1979-05 Impact factor: 3.765

The regeneration of rectal epithelium in the rat following wounding with suppositories of polyoxyethylene (23) lauryl ether.

1. A histochemical study of regenerating large bowel epithelium.

2. Normal human rectal mucosa and its mechanism of repair.

3. Regeneration of the mucosa of the colon following its removal in short segments of the bowel: an experimental study.

4. Mucosal repair in the rectum.

5. Mitotic activity of epithelial cells in wounded rectal mucous membrane.

6. Regeneration of the human colon mucosa. Morphological and histochemical study.

7. Wounds and wound healing.

8. Relative effects of different surfactants on intestinal absorption and the release of proteins and phospholipids from the tissue.

9. Colon mucosa response to injury. I. Morphological study.

10. An electron microscopical study of chronic ulcers of the colon in rats.

1. Blood flow to the rat rectum: its intramural distribution and the response to injury.

2. Rectal mucosa damage in rabbits after subchronical application of suppository bases.

3. Epithelial restitution in the large intestine of the rat following insult with bile salts.