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Literature DB >> 6613746

Muscarinic cholinergic receptor binding in rat mast cells.

E Masini, R Fantozzi, P Blandina, S Brunelleschi, P F Mannaioni.

Abstract

Specific [3H]-QNB binding was present in isolated, purified, intact rat mast cells and in crude membrane preparations. The binding is saturable, time- and temperature-dependent. Cholinergic agents inhibit selectively the binding: atropine is the most effective of the antagonists while oxotremorine is the most potent of the muscarinic agonists. It is concluded that rat mast cells are provided with muscarinic cholinergic receptors.

Entities: Chemical Species

Mesh：

Substances：

Year: 1983 PMID： 6613746 DOI： 10.1007/bf01971484

Source DB: PubMed Journal: Agents Actions ISSN： 0065-4299

24 in total

1. Ligand binding to muscarinic receptors in intact longitudinal muscle strips from guinea-pig intestine.

Authors: D Ward; J M Young
Journal: Br J Pharmacol Date: 1977-10 Impact factor: 8.739

2. Muscarinic acetylcholine receptors interactions: competition binding studies with agonists and antagonists.

Authors: Y Kloog; M Sokolovsky
Journal: Brain Res Date: 1977-09-23 Impact factor: 3.252

Review 3. The pharmacological control of immediate hypersensitivity.

Authors: J C Foreman
Journal: Annu Rev Pharmacol Toxicol Date: 1981 Impact factor: 13.820

4. Properties of the muscarinic cholinergic receptors in rat atrium.

Authors: J W Wei; P V Sulakhe
Journal: Naunyn Schmiedebergs Arch Pharmacol Date: 1979-11 Impact factor: 3.000

5. Cardiac muscarinic cholinergic receptors. Biochemical identification and characterization.

Authors: J Z Fields; W R Roeske; E Morkin; H I Yamamura
Journal: J Biol Chem Date: 1978-05-10 Impact factor: 5.157

6. Identification of muscarinic binding sites in human neutrophils by direct binding.

Authors: B H Dulis; M A Gordon; I B Wilson
Journal: Mol Pharmacol Date: 1979-01 Impact factor: 4.436

7. The effects of ions on the binding of agonists and antagonists to muscarinic receptors.

Authors: N J Birdsall; A S Burgen; E C Hulme; J W Wells
Journal: Br J Pharmacol Date: 1979-11 Impact factor: 8.739

8. Characteristics of histamine release evoked by acetylcholine in isolated rat mast cells.

Authors: P Blandina; R Fantozzi; P F Mannaioni; E Masini
Journal: J Physiol Date: 1980-04 Impact factor: 5.182

9. [3H]-Quinuclidinyl benzilate binding to muscarinic receptors in rat brain: comparison of results from intact brain slices and homogenates.

Authors: R F Gilbert; M R Hanley; L L Iversen
Journal: Br J Pharmacol Date: 1979-03 Impact factor: 8.739

10. Temperature coefficients of affinity and entropies of adsorption from enantiomeric pairs of compounds acting at muscarinic receptors in the guinea-pig ileum.

Authors: R B Barlow; K N Burston
Journal: Br J Pharmacol Date: 1979-08 Impact factor: 8.739

6 in total

Muscarinic cholinergic receptor binding in rat mast cells.

1. Ligand binding to muscarinic receptors in intact longitudinal muscle strips from guinea-pig intestine.

2. Muscarinic acetylcholine receptors interactions: competition binding studies with agonists and antagonists.

Review 3. The pharmacological control of immediate hypersensitivity.

4. Properties of the muscarinic cholinergic receptors in rat atrium.

5. Cardiac muscarinic cholinergic receptors. Biochemical identification and characterization.

6. Identification of muscarinic binding sites in human neutrophils by direct binding.

7. The effects of ions on the binding of agonists and antagonists to muscarinic receptors.

8. Characteristics of histamine release evoked by acetylcholine in isolated rat mast cells.

9. [3H]-Quinuclidinyl benzilate binding to muscarinic receptors in rat brain: comparison of results from intact brain slices and homogenates.

10. Temperature coefficients of affinity and entropies of adsorption from enantiomeric pairs of compounds acting at muscarinic receptors in the guinea-pig ileum.

Review 1. Interactions of mast cells with the nervous system--recent advances.

2. Central muscarinic cholinergic regulation of the systemic inflammatory response during endotoxemia.

3. The release of histamine by parasympathetic stimulation in guinea-pig auricle and rat ileum.

4. Histamine release by vagal stimulation.

Review 5. Cholinergic Modulation of Type 2 Immune Responses.

6. Neuro-Immune Modulation Effects of Sacral Nerve Stimulation for Visceral Hypersensitivity in Rats.