Literature DB >> 6606157

Dialkylformamidines: depurination resistant N6-protecting group for deoxyadenosine.

B C Froehler, M D Matteucci.   

Abstract

Sterically hindered N6-dialkylformamidine protected deoxyadenosine is more stable to acidic depurination than N6-benzoyldeoxyadenosine and is potentially a valuable protecting group in the synthesis of deoxyoligonucleotides.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6606157      PMCID： PMC326557          DOI： 10.1093/nar/11.22.8031

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  3 in total

1.  Selective N-debenzoylation of N,O-polybenzoylucleosides.

Authors:  R L Letsinger; P S Miller; G W Grams
Journal:  Tetrahedron Lett       Date:  1968-04       Impact factor: 2.415

2.  Synthesis of oligodeoxyribonucleotides on silica gel support.

Authors:  F Chow; T Kempe; G Palm
Journal:  Nucleic Acids Res       Date:  1981-06-25       Impact factor: 16.971

3.  Syringe method for stepwise chemical synthesis of oligonucleotides.

Authors:  T Tanaka; R L Letsinger
Journal:  Nucleic Acids Res       Date:  1982-05-25       Impact factor: 16.971
  3 in total
  26 in total

1.  A spectroscopic and calorimetric study of the melting behaviors of a "bent" and a "normal" DNA duplex: [d(GA4T4C)]2 versus [d(GT4A4C)]2.

Authors:  Y W Park; K J Breslauer
Journal:  Proc Natl Acad Sci U S A       Date:  1991-02-15       Impact factor: 11.205

Review 2.  Fluorescent analogs of biomolecular building blocks: design, properties, and applications.

Authors:  Renatus W Sinkeldam; Nicholas J Greco; Yitzhak Tor
Journal:  Chem Rev       Date:  2010-05-12       Impact factor: 60.622

3.  Oligodeoxynucleotides containing C-7 propyne analogs of 7-deaza-2'-deoxyguanosine and 7-deaza-2'-deoxyadenosine.

Authors:  C A Buhr; R W Wagner; D Grant; B C Froehler
Journal:  Nucleic Acids Res       Date:  1996-08-01       Impact factor: 16.971

4.  Highly efficient synthesis of oligodeoxyribonucleotides using alpha-phenyl cinnamoyl group for selective amino protection.

Authors:  A K Nagaich; K Misra
Journal:  Nucleic Acids Res       Date:  1989-07-11       Impact factor: 16.971

5.  Improved synthesis of oligodeoxyribonucleotide using 3-methoxy-4-phenoxybenzoyl group for amino protection.

Authors:  R K Mishra; K Misra
Journal:  Nucleic Acids Res       Date:  1986-08-11       Impact factor: 16.971

6.  Synthesis and properties of defined DNA oligomers containing base mispairs involving 2-aminopurine.

Authors:  R Eritja; B E Kaplan; D Mhaskar; L C Sowers; J Petruska; M F Goodman
Journal:  Nucleic Acids Res       Date:  1986-07-25       Impact factor: 16.971

7.  Synthesis of conformationally locked versions of puromycin analogues.

Authors:  Hisao Saneyoshi; Benoît Y Michel; Yongseok Choi; Peter Strazewski; Victor E Marquez
Journal:  J Org Chem       Date:  2008-12-05       Impact factor: 4.354

8.  A new, but old, nucleoside analog: the first synthesis of 1-deaza-2'-deoxyguanosine and its properties as a nucleoside and as oligodeoxynucleotides.

Authors:  Naoshi Kojima; Kaori Inoue; Rina Nakajima-Shibata; Shun-ichi Kawahara; Eiko Ohtsuka
Journal:  Nucleic Acids Res       Date:  2003-12-15       Impact factor: 16.971

9.  Synthesis of high-quality libraries of long (150mer) oligonucleotides by a novel depurination controlled process.

Authors:  Emily M LeProust; Bill J Peck; Konstantin Spirin; Heather Brummel McCuen; Bridget Moore; Eugeni Namsaraev; Marvin H Caruthers
Journal:  Nucleic Acids Res       Date:  2010-03-22       Impact factor: 16.971

10.  Synthesis of DNA via deoxynucleoside H-phosphonate intermediates.

Authors:  B C Froehler; P G Ng; M D Matteucci
Journal:  Nucleic Acids Res       Date:  1986-07-11       Impact factor: 16.971
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.