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Literature DB >> 6602468

The effect of coumarin derivatives on the immunological system of man.

B Berkarda, H Bouffard-Eyüboğlu, U Derman.

Abstract

Peripheral blood lymphocyte mitogen responsiveness was studied in 12 normal and 51 cancer patients. One group of patients was treated with warfarin, the second group with coumarin. There was a significant increase in lymphocyte response to phytohaemagglutinin (PHA) following both drugs. This increase indicates that both agents are capable of activating lymphocytes and thus stimulating some immunological functions.

Entities: Chemical Disease Species

Mesh：

Substances：
Coumarins
Warfarin

Year: 1983 PMID： 6602468 DOI： 10.1007/bf01994281

Source DB: PubMed Journal: Agents Actions ISSN： 0065-4299

12 in total

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Journal: Arch Surg Date: 1962-04

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Journal: Nature Date: 1974-08-23 Impact factor: 49.962

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Journal: Scand J Clin Lab Invest Suppl Date: 1968

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Authors: J M Brown
Journal: Cancer Res Date: 1973-06 Impact factor: 12.701

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Authors: A S Ketcham; E V Sugarbaker; J J Ryan; S K Orme
Journal: Am J Roentgenol Radium Ther Nucl Med Date: 1971-01

6. The induction of controlled proteolysis in high protein oedemas by coumarin.

Authors: N B Piller
Journal: Z Lymphol Date: 1979-12

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Authors: P Alexander
Journal: Schweiz Med Wochenschr Date: 1976-10-02

8. Influence of anti-inflammatory drugs on the interaction of lymphocytes and macrophages.

Authors: H Mullink; M von Blomberg
Journal: Agents Actions Date: 1980-12

9. Warfarin treatment of mice bearing autochthonous tumors: effect on spontaneous metastases.

Authors: J J Ryan; A S Ketcham; H Wexler
Journal: Science Date: 1968-12-27 Impact factor: 47.728

10. A morphological assessment of the stimulatory effect of coumarin on macrophages.

Authors: N B Piller
Journal: Br J Exp Pathol Date: 1978-02

26 in total

1. A comparison of US and Norwegian regulation of coumarin in tobacco products.

Authors: M Givel
Journal: Tob Control Date: 2003-12 Impact factor: 7.552

2. The Bacterial Community of the Foliose Macro-lichen Peltigera frigida Is More than a Mere Extension of the Microbiota of the Subjacent Substrate.

Authors: Diego Leiva; Fernando Fernández-Mendoza; José Acevedo; Margarita Carú; Martin Grube; Julieta Orlando
Journal: Microb Ecol Date: 2021-01-06 Impact factor: 4.552

3. Mode of action of coumarin in immune cells.

Authors: G J Zlabinger; C Nöhammer; G A Böhmig; J E Menzel
Journal: J Cancer Res Clin Oncol Date: 1994 Impact factor: 4.553

4. The Chemosensory Repertoire of the Eastern Diamondback Rattlesnake (Crotalus adamanteus) Reveals Complementary Genetics of Olfactory and Vomeronasal-Type Receptors.

Authors: Michael P Hogan; A Carl Whittington; Michael B Broe; Micaiah J Ward; H Lisle Gibbs; Darin R Rokyta
Journal: J Mol Evol Date: 2021-04-21 Impact factor: 2.395