Literature DB >> 5700070

Warfarin treatment of mice bearing autochthonous tumors: effect on spontaneous metastases.

J J Ryan, A S Ketcham, H Wexler.   

Abstract

Long-term oral administration of sodium warfarin significantly reduced the incidence of spontaneous metastases in the lungs from 83 percent in controls to 8 percent in treated C57/BL/6N mice. The size and weight of primary tumors in mice treated with warfarin were less than in control mice. Length of survival was unaffected.

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Year:  1968        PMID: 5700070     DOI: 10.1126/science.162.3861.1493

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  12 in total

1.  Aspirin for reducing cancer metastases?

Authors:  U K Henschke; G J Luande; J D Choppala
Journal:  J Natl Med Assoc       Date:  1977-08       Impact factor: 1.798

2.  Synergistic effect of coumarin (1,2 benzopyrone) and endotoxin in the induction of human interleukin-1.

Authors:  K Stuhlmeier; G Theyer; G Baumgartner; G J Zlabinger
Journal:  Clin Exp Immunol       Date:  1991-05       Impact factor: 4.330

3.  Effect of warfarin on cell kinetics, epithelial morphology and tumour incidence in induced colorectal cancer in the rat.

Authors:  N Goeting; G A Trotter; T Cooke; N Kirkham; I Taylor
Journal:  Gut       Date:  1985-08       Impact factor: 23.059

4.  The effect of coumarin derivatives on the immunological system of man.

Authors:  B Berkarda; H Bouffard-Eyüboğlu; U Derman
Journal:  Agents Actions       Date:  1983-02

Review 5.  Fibrin as a component of the tumor stroma: origins and biological significance.

Authors:  H F Dvorak; D R Senger; A M Dvorak
Journal:  Cancer Metastasis Rev       Date:  1983       Impact factor: 9.264

Review 6.  [The significance of fibrin/fibrinogen for growth and metastasis of malignant tumors (author's transl)].

Authors:  H Heyes; D Glück
Journal:  Klin Wochenschr       Date:  1977-11-15

7.  Anticoagulants and experimental metastases-evaluation of antimetastatic effects in different model systems.

Authors:  B Maat; P Hilgard
Journal:  J Cancer Res Clin Oncol       Date:  1981       Impact factor: 4.553

8.  Apoptotic Bodies Elicit Gas6-Mediated Migration of AXL-Expressing Tumor Cells.

Authors:  Annelien J M Zweemer; Cory B French; Joshua Mesfin; Simon Gordonov; Aaron S Meyer; Douglas A Lauffenburger
Journal:  Mol Cancer Res       Date:  2017-09-18       Impact factor: 5.852

9.  Association of Vitamin K and Non-Vitamin K Oral Anticoagulant Use and Cancer Incidence in Atrial Fibrillation Patients.

Authors:  Adina A Iftimi; Clara L Rodríguez-Bernal; Salvador Peiró; Santiago Bonanad; Andreu Ferrero-Gregori; Isabel Hurtado; Aníbal García-Sempere; Gabriel Sanfélix-Gimeno
Journal:  Clin Pharmacol Ther       Date:  2021-07-26       Impact factor: 6.903

10.  Warfarin inhibits metastasis of Mtln3 rat mammary carcinoma without affecting primary tumour growth.

Authors:  P McCulloch; W D George
Journal:  Br J Cancer       Date:  1989-02       Impact factor: 7.640

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