Literature DB >> 6572946

Histone mRNA concentrations are regulated at the level of transcription and mRNA degradation.

D B Sittman, R A Graves, W F Marzluff.   

Abstract

The levels of histone mRNA are rapidly reduced after treatment of cultured cells with hydroxyurea or cytosine arabinonucleoside. The histone mRNA for the replicative histone variants is destroyed rapidly, with a half-life of 10-15 min. The levels of mRNA coding for the replacement histone variant H3.3 were unchanged after treatment with DNA synthesis inhibitors. In addition to the rapid destruction of histone mRNA, there was a reduction to 1/5th in the rate of transcription of the histone genes. Lymphoma cells (S49) arrested in G1 by cyclic AMP produce and contain significant levels of histone mRNA. Hydroxyurea reduces the rate of transcription and the levels of histone mRNA in the G1-arrested cells.

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Year:  1983        PMID： 6572946      PMCID： PMC393707          DOI： 10.1073/pnas.80.7.1849

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  26 in total

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Authors:  M Breindl; D Gallwitz
Journal:  Eur J Biochem       Date:  1973-01-15

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Authors:  W F Marzluff; E C Murphy; R C Huang
Journal:  Biochemistry       Date:  1973-08-28       Impact factor: 3.162

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Authors:  W B Butler; G C Mueller
Journal:  Biochim Biophys Acta       Date:  1973-02-04

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Authors:  L R Gurley; R A Walters; R A Tobey
Journal:  Arch Biochem Biophys       Date:  1972-02       Impact factor: 4.013

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Authors:  D Gallwitz; G C Mueller
Journal:  J Biol Chem       Date:  1969-11-10       Impact factor: 5.157

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Authors:  D Gallwitz; G C Mueller
Journal:  Science       Date:  1969-03-21       Impact factor: 47.728

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Authors:  T W Borun; M D Scharff; E Robbins
Journal:  Proc Natl Acad Sci U S A       Date:  1967-11       Impact factor: 11.205

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Authors:  S G Franklin; A Zweidler
Journal:  Nature       Date:  1977-03-17       Impact factor: 49.962

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Authors:  H Stahl; D Gallwitz
Journal:  Eur J Biochem       Date:  1977-01

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Authors:  J M Kinkade; R D Cole
Journal:  J Biol Chem       Date:  1966-12-25       Impact factor: 5.157
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  133 in total

1.  Intronless mRNA transport elements may affect multiple steps of pre-mRNA processing.

Authors:  Y Huang; K M Wimler; G G Carmichael
Journal:  EMBO J       Date:  1999-03-15       Impact factor: 11.598

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Authors:  R E Wager; R K Assoian
Journal:  Mol Cell Biol       Date:  1990-11       Impact factor: 4.272

3.  The histone mRNA 3' end is required for localization of histone mRNA to polyribosomes.

Authors:  J Sun; D R Pilch; W F Marzluff
Journal:  Nucleic Acids Res       Date:  1992-11-25       Impact factor: 16.971

4.  Origins and formation of histone methylation across the human cell cycle.

Authors:  Barry M Zee; Laura-Mae P Britton; Daniel Wolle; Devorah M Haberman; Benjamin A Garcia
Journal:  Mol Cell Biol       Date:  2012-04-30       Impact factor: 4.272

5.  U7 small nuclear ribonucleoprotein represses histone gene transcription in cell cycle-arrested cells.

Authors:  Takashi Ideue; Shungo Adachi; Takao Naganuma; Akie Tanigawa; Tohru Natsume; Tetsuro Hirose
Journal:  Proc Natl Acad Sci U S A       Date:  2012-03-26       Impact factor: 11.205

6.  Role of oligouridylation in normal metabolism and regulated degradation of mammalian histone mRNAs.

Authors:  Stacie A Meaux; Christopher E Holmquist; William F Marzluff
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2018-11-05       Impact factor: 6.237

7.  Dynamic regulation of histone modifications in Xenopus oocytes through histone exchange.

Authors:  M David Stewart; John Sommerville; Jiemin Wong
Journal:  Mol Cell Biol       Date:  2006-09       Impact factor: 4.272

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Authors:  L Yu; M A Gorovsky
Journal:  Mol Cell Biol       Date:  1997-11       Impact factor: 4.272

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Authors:  D Brush; J B Dodgson; O R Choi; P W Stevens; J D Engel
Journal:  Mol Cell Biol       Date:  1985-06       Impact factor: 4.272

10.  A unique subspecies of histone H4 mRNA from rat myoblasts contains poly(A).

Authors:  R C Bird; F A Jacobs; G Stein; J Stein; B H Sells
Journal:  Proc Natl Acad Sci U S A       Date:  1985-10       Impact factor: 11.205
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