| Literature DB >> 6572416 |
M B Sporn, A B Roberts, J H Shull, J M Smith, J M Ward, J Sodek.
Abstract
Transforming growth factors, which are polypeptides that induce the transformed phenotype in nonneoplastic cells, have been isolated in bulk amounts from bovine salivary gland and kidney. In experiments in which wound healing chambers were implanted subcutaneously in the backs of rats, these bovine transforming growth factors accelerated the accumulation of total protein, collagen, and DNA in treated chambers. These studies thus show an effect of an isolated transforming growth factor in vivo.Entities:
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Year: 1983 PMID: 6572416 DOI: 10.1126/science.6572416
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728