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Literature DB >> 6568200

Two new Bf S subtypes revealed by isoelectric focusing and immunofixation.

S Weidinger, F Schwarzfischer, R Burgemeister, H Cleve.

Abstract

The genetic types of the properdin factor B were analyzed by isoelectric focusing on polyacrylamide gels and subsequent immunofixation. Sera from 516 unrelated, healthy individuals from Southern Germany were examined. Two new subtypes of the Bf*S allele were observed. They were provisionally named Bf*Sb1 and Bf*Sb2(b = basic), since the position of their bands is located slightly towards the cathode. Whereas Bf Sb2 has, thus far, been found only in a single individual, Bf Sb1 was found in five unrelated persons and in a mother and her child indicating a simple codominant mode of inheritance. The combined frequency of the Bf*Sb alleles was calculated to be 0.0067.

Entities: Chemical Gene Species

Mesh：

Substances：

Year: 1984 PMID： 6568200 DOI： 10.1007/bf00293880

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

16 in total

1. Localization of the Bf locus within the HLA region. Report on an informative family and critical evaluation of available data on Bf mapping.

Authors: C Rittner; H Grosse-Wilde; E D Albert
Journal: Hum Genet Date: 1976-12-29 Impact factor: 4.132

2. The localization of the Bf locus within the MHS region on chromosome no. 6.

Authors: G Hauptmann; M Sasportes; M M Tongio; S Mayer; J Dausset
Journal: Tissue Antigens Date: 1976-01

3. Bf polymorphism: another variant (S0.8).

Authors: G Hauptmann; E Wertheimer; M M Tongio; S Mayer
Journal: Hum Genet Date: 1977-04-07 Impact factor: 4.132

4. Linkage of HL-A and GBG.

Authors: F H Allen
Journal: Vox Sang Date: 1974 Impact factor: 2.144

5. A hemolytically inactive gene product of factor B.

Authors: G Mauff; G Federmann; G Hauptmann
Journal: Immunobiology Date: 1980 Impact factor: 3.144

6. Complement loci of the HLA complex. Studies on families with intra-HLA crossovers and haplotype associations.

Authors: B Olaisen; P Teisberg; R Jonassen; T Gedde-Dahl; T Moen; E Thorsby
Journal: Hum Immunol Date: 1981-05 Impact factor: 2.850

7. Linkage group HL-A-MLC-BF (properdin factor B). The site of the Bf locus at the immunogenetic linkage group on chromosome 6.

Authors: C Rittner; H Grosse-Wilde; B Netzel; S Scholz; H Lorenz; E D Albert
Journal: Humangenetik Date: 1975

Two new Bf S subtypes revealed by isoelectric focusing and immunofixation.

1. Localization of the Bf locus within the HLA region. Report on an informative family and critical evaluation of available data on Bf mapping.

2. The localization of the Bf locus within the MHS region on chromosome no. 6.

3. Bf polymorphism: another variant (S0.8).

4. Linkage of HL-A and GBG.

5. A hemolytically inactive gene product of factor B.

6. Complement loci of the HLA complex. Studies on families with intra-HLA crossovers and haplotype associations.

7. Linkage group HL-A-MLC-BF (properdin factor B). The site of the Bf locus at the immunogenetic linkage group on chromosome 6.

8. Properdin factor B-polymorphism. An indication for the existence of a Bf O-allele.

9. Properdin factor B (Bf) polymorphism: subtyping of SS phenotypes.

10. Subtyping of properdin factor B (Bf) by isoelectrofocusing.

1. Nomenclature for human complement factor B. WHO-IUIS Nomenclature Sub-Committee.

2. Factor B subtyping in sera and bloodstains by isoelectric focusing and immunoblotting.

3. Human BF*F-subtypes: segregation analysis with inclusion of MHC haplotypes.

4. A new BF F variant by polyacrylamide gel isoelectric focusing.