| Literature DB >> 6525334 |
E Taillandier, J A Taboury, S Adam, J Liquier.
Abstract
Infrared spectroscopic studies demonstrate the ability of poly[d(A-C)].poly[d(G-T)] to adopt a Z-type conformation. The Z form of the unmodified polynucleotide is induced by Ni2+ counterions and not by Na+. The B----Z equilibrium is shifted at room temperature, in the presence of 1 Ni2+/nucleotide, by an increase in the concentration of poly[d(A-C)].poly[d(G-T)]. The importance of specific binding of Ni2+ ions on the N7 site of purines in the stabilization of the Z form is also discussed.Entities:
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Year: 1984 PMID: 6525334 DOI: 10.1021/bi00319a007
Source DB: PubMed Journal: Biochemistry ISSN: 0006-2960 Impact factor: 3.162