Literature DB >> 6513929

Molecular cloning and chromosomal assignment of the human homolog of int-1, a mouse gene implicated in mammary tumorigenesis.

L J van 't Veer, A G van Kessel, H van Heerikhuizen, A van Ooyen, R Nusse.   

Abstract

Viral mammary tumorigenesis in mice is frequently initiated by proviral activation of a highly conserved cellular gene called int-1. We have cloned the human homolog of this putative mammary oncogene and compared its structure to that of the mouse gene by heteroduplex analysis. The human int-1 gene was localized on chromosome 12 by use of somatic cell hybrids.

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Year:  1984        PMID： 6513929      PMCID： PMC369085          DOI： 10.1128/mcb.4.11.2532-2534.1984

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  12 in total

1.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

2.  Multiple arrangements of viral DNA and an activated host oncogene in bursal lymphomas.

Authors:  G S Payne; J M Bishop; H E Varmus
Journal:  Nature       Date:  1982-01-21       Impact factor: 49.962

3.  Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis.

Authors:  W S Hayward; B G Neel; S M Astrin
Journal:  Nature       Date:  1981-04-09       Impact factor: 49.962

4.  Chromosomal assignment of a family of human oncogenes.

Authors:  J Ryan; P E Barker; K Shimizu; M Wigler; F H Ruddle
Journal:  Proc Natl Acad Sci U S A       Date:  1983-07       Impact factor: 11.205

5.  Regional chromosomal localization of N-ras, K-ras-1, K-ras-2 and myb oncogenes in human cells.

Authors:  O W McBride; D C Swan; S R Tronick; R Gol; D Klimanis; D E Moore; S A Aaronson
Journal:  Nucleic Acids Res       Date:  1983-12-10       Impact factor: 16.971

6.  Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome.

Authors:  R Nusse; H E Varmus
Journal:  Cell       Date:  1982-11       Impact factor: 41.582

7.  Human c-Ki-ras2 proto-oncogene on chromosome 12.

Authors:  A Y Sakaguchi; S L Naylor; T B Shows; J J Toole; M McCoy; R A Weinberg
Journal:  Science       Date:  1983-03-04       Impact factor: 47.728

8.  The chromosomal basis of human neoplasia.

Authors:  J J Yunis
Journal:  Science       Date:  1983-07-15       Impact factor: 47.728

9.  Activation of the cellular oncogene c-erbB by LTR insertion: molecular basis for induction of erythroblastosis by avian leukosis virus.

Authors:  Y K Fung; W G Lewis; L B Crittenden; H J Kung
Journal:  Cell       Date:  1983-06       Impact factor: 41.582

10.  Tumorigenesis by mouse mammary tumor virus: evidence for a common region for provirus integration in mammary tumors.

Authors:  G Peters; S Brookes; R Smith; C Dickson
Journal:  Cell       Date:  1983-06       Impact factor: 41.582
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  14 in total

1.  Structural alteration in the MYB protooncogene and deletion within the gene encoding alpha-type protein kinase C in human melanoma cell lines.

Authors:  A J Linnenbach; K Huebner; E P Reddy; M Herlyn; A H Parmiter; P C Nowell; H Koprowski
Journal:  Proc Natl Acad Sci U S A       Date:  1988-01       Impact factor: 11.205

2.  Chromosomal localization of three human genes encoding members of the TGF-beta superfamily of type I serine/threonine kinase receptors.

Authors:  E Röijer; K Miyazono; A K Aström; A Geurts van Kessel; P ten Dijke; G Stenman
Journal:  Mamm Genome       Date:  1998-03       Impact factor: 2.957

Review 3.  The cell survival pathways of the primordial RNA-DNA complex remain conserved in the extant genomes and may function as proto-oncogenes.

Authors:  J G Sinkovics
Journal:  Eur J Microbiol Immunol (Bp)       Date:  2015-03-26

4.  Isolation of a human genomic fragment, co-amplified with c-Ki-ras, that affects plasmid supercoiling in E. coli.

Authors:  J Heighway; A H Geurts van Kessel
Journal:  Nucleic Acids Res       Date:  1987-04-24       Impact factor: 16.971

5.  Characterization and chromosome assignment of the human homolog of int-2, a potential proto-oncogene.

Authors:  G Casey; R Smith; D McGillivray; G Peters; C Dickson
Journal:  Mol Cell Biol       Date:  1986-02       Impact factor: 4.272

6.  Two type II keratin genes are localized on human chromosome 12.

Authors:  N C Popescu; P E Bowden; J A DiPaolo
Journal:  Hum Genet       Date:  1989-05       Impact factor: 4.132

7.  The human gene encoding insulin-like growth factor I is located on chromosome 12.

Authors:  J W Höppener; P de Pagter-Holthuizen; A H Geurts van Kessel; M Jansen; S D Kittur; S E Antonarakis; C J Lips; J S Sussenbach
Journal:  Hum Genet       Date:  1985       Impact factor: 4.132

8.  Nucleotide sequence and expression in vitro of cDNA derived from mRNA of int-1, a provirally activated mouse mammary oncogene.

Authors:  Y K Fung; G M Shackleford; A M Brown; G S Sanders; H E Varmus
Journal:  Mol Cell Biol       Date:  1985-12       Impact factor: 4.272

9.  INT2 and ERBB2 amplification and ERBB2 expression in breast tumors from patients with different outcomes.

Authors:  R J Pauley; P A Gimotty; T J Paine; P J Dawson; S R Wolman
Journal:  Breast Cancer Res Treat       Date:  1996       Impact factor: 4.872

Review 10.  Wingless Signaling: A Genetic Journey from Morphogenesis to Metastasis.

Authors:  Amy Bejsovec
Journal:  Genetics       Date:  2018-04       Impact factor: 4.562
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