| Literature DB >> 2982726 |
J W Höppener, P de Pagter-Holthuizen, A H Geurts van Kessel, M Jansen, S D Kittur, S E Antonarakis, C J Lips, J S Sussenbach.
Abstract
A cDNA probe corresponding to mRNA encoding human somatomedin-C/insulin-like growth factor I (IGF-I) was used for the chromosomal assignment of the IGF-I gene. Southern-blot hybridization analysis of DNA from human-Chinese hamster somatic cell hybrids showed that the IGF-I gene is located on chromosome 12. Comparison of the chromosomal assignments of the IGF-I gene and two other members of the insulin gene family, with three c-ras oncogenes, reveals a remarkable association of the two gene families.Entities:
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Year: 1985 PMID： 2982726 DOI： 10.1007/bf00293288
Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132