Literature DB >> 6504698

Studies on the conformation and dynamics of the C8-substituted guanine adduct of the carcinogen acetylaminofluorene; model for a possible Z-DNA modified structure.

S Neidle, R Kuroda, S Broyde, B E Hingerty, R A Levine, D W Miller, F E Evans.   

Abstract

The structure of an adduct between guanine and the carcinogen acetylaminofluorene has been examined in the solid state by X-ray crystallography, and in solution by NMR techniques. The observed conformations have been compared with predictions from energy calculations and their relevance to models of adducts with DNA has been examined.

Entities:  

Mesh：

Substances：

Year:  1984        PMID： 6504698      PMCID： PMC320303          DOI： 10.1093/nar/12.21.8219

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  16 in total

1.  Physical studies on deoxyribonucleic acid after covalent binding of a carcinogen.

Authors:  R Fuchs; M Daune
Journal:  Biochemistry       Date:  1972-07-04       Impact factor: 3.162

2.  Conformation of acetylaminofluorene and aminofluorene modified guanosine and guanosine derivatives.

Authors:  M Leng; M Ptak; P Rio
Journal:  Biochem Biophys Res Commun       Date:  1980-10-16       Impact factor: 3.575

3.  8-(N-2-fluorenylacetamido)guanosine, an arylamidation reaction product of guanosine and the carcinogen N-acetoxy-N-2-fluorenylacetamide in neutral solution.

Authors:  E Kriek; J A Miller; U Juhl; E C Miller
Journal:  Biochemistry       Date:  1967-01       Impact factor: 3.162

4.  Circular dichroism and proton magnetic resonance studies of dApdG modified with 2-aminofluorene and 2-acetylaminofluorene.

Authors:  R M Santella; E Kriek; D Grunberger
Journal:  Carcinogenesis       Date:  1980       Impact factor: 4.944

5.  Acyltransferase-mediated binding of N-hydroxyarylamides to nucleic acids.

Authors:  F A Beland; W T Allaben; F E Evans
Journal:  Cancer Res       Date:  1980-03       Impact factor: 12.701

6.  Left-handed double helical DNA: variations in the backbone conformation.

Authors:  A J Wang; G J Quigley; F J Kolpak; G van der Marel; J H van Boom; A Rich
Journal:  Science       Date:  1981-01-09       Impact factor: 47.728

7.  Structural identification of the pyrimidine derivatives formed from N-(deoxyguanosin-8-yl)-2-aminofluorene in aqueous solution at alkaline pH.

Authors:  E Kriek; J G Westra
Journal:  Carcinogenesis       Date:  1980-06       Impact factor: 4.944

8.  Coding and conformational properties of oligonucleotides modified with the carcinogen N-2-acetylaminofluorene.

Authors:  D Grunberger; J H Nelson; C R Cantor; I B Weinstein
Journal:  Proc Natl Acad Sci U S A       Date:  1970-06       Impact factor: 11.205

9.  Induction of the Z conformation in poly(dG-dC).poly(dG-dC) by binding of N-2-acetylaminofluorene to guanine residues.

Authors:  R M Santella; D Grunberger; I B Weinstein; A Rich
Journal:  Proc Natl Acad Sci U S A       Date:  1981-03       Impact factor: 11.205

10.  9-beta-D-Arabinofuranosyl-8-n-butylaminoadenine, a C-8 substituted nucleoside in the anti conformation. Crystallographic and NMR studies.

Authors:  S Neidle; M R Sanderson; A Subbiah; J B Chattopadhyaya; R Kuroda; C B Reese
Journal:  Biochim Biophys Acta       Date:  1979-12-17
View more
  4 in total

1.  Visualization of an AAF induced frameshift mutation: molecular views of base displacement in B-DNA from minimized potential energy calculations.

Authors:  S Broyde; B E Hingerty
Journal:  Nucleic Acids Res       Date:  1987-08-25       Impact factor: 16.971

2.  AM1 Study of N-2-Acetylaminofluorene bonded to Deoxyguanosine at the Minor Adduct Site.

Authors:  M Besson; E P Batchelor
Journal:  J Biol Phys       Date:  2004-06       Impact factor: 1.365

3.  Structure of oxidatively damaged nucleic acid adducts. 3. Tautomerism, ionization and protonation of 8-hydroxyadenosine studied by 15N NMR spectroscopy.

Authors:  B P Cho; F E Evans
Journal:  Nucleic Acids Res       Date:  1991-03-11       Impact factor: 16.971

4.  Nucleotide excision repair of 2-acetylaminofluorene- and 2-aminofluorene-(C8)-guanine adducts: molecular dynamics simulations elucidate how lesion structure and base sequence context impact repair efficiencies.

Authors:  Hong Mu; Konstantin Kropachev; Lihua Wang; Lu Zhang; Alexander Kolbanovskiy; Marina Kolbanovskiy; Nicholas E Geacintov; Suse Broyde
Journal:  Nucleic Acids Res       Date:  2012-08-16       Impact factor: 16.971
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.